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Study · Measured the body's own peptide · 2007

1 result

Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder.

Brundin L, Björkqvist M, Petersén A, Träskman-Bendz L

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology7 Mar 2007Cited by 172 (Europe PMC)

PMID17346943 (opens in a new tab)DOI10.1016/j.euroneuro.2007.01.005 (opens in a new tab)PepBankPUB-17346943
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In 66 patients with depressive disorders after a suicide attempt, CSF orexin-A correlated significantly with the body's own CSF DSIP-like immunoreactivity.

    In plain wordsIn patients after a suicide attempt, spinal fluid orexin was linked to the body's own DSIP-like levels.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableCorrelation of CSF orexin-A with CSF DSIP-like immunoreactivity
    Study

    n = 66

    Outcome group
    Endogenous peptide levels · Mental health and mood

    Source sentences

    Summary
    Orexin correlated significantly with CSF levels of somatostatin, delta sleep inducing peptide-like immunoreactivity (DSIP-LI) and corticotrophin releasing factor (CRF), but not with leptin or vasopressin.
    1 context sentence
    Summary · context
    We measured orexin-A in the cerebrospinal fluid (CSF) of 66 patients with major depressive disorder (MDD), dysthymia and adjustment disorder after a suicide attempt.

    This result measures the body's own Delta sleep-inducing peptide (DSIP). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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