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Study · Not a test of the peptide alone · 2007

3 results

Antioxidant properties of geroprotective peptides of the pineal gland.

Kozina LS, Arutjunyan AV, Khavinson VKh

Archives of gerontology and geriatrics1 Jan 2007Cited by 14 (Europe PMC)

PMID17317455 (opens in a new tab)DOI10.1016/j.archger.2007.01.029 (opens in a new tab)PepBankPUB-17317455
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Epitalon.

  1. 01AnimalNot a test of Epitalon aloneAnimal study (in vivo)Activity measurement

    In old rats, the pineal peptide preparations, including epitalon, had antioxidant properties that in some cases exceeded those of melatonin.

    In plain wordsIn old rats, pineal peptide preparations, including epitalon, showed antioxidant effects that sometimes exceeded those of melatonin.

    Peptide
    Epitalon
    Outcome
    IncreaseAntioxidant properties compared with melatonin
    Study

    ratn: not reported in source

    Old rats (blood serum, liver and brain)
    Comparator
    Melatonin
    Outcome group
    Oxidative stress · Aging and longevity

    Source sentences

    Summary
    It was shown that peptide preparations from the pineal gland (epithalamin and epitalon) possess antioxidant properties exceeding in some cases the effects of the well-known scavenger of reactive oxygen species (ROS), the melatonin, which is also produced by the pineal gland.
    1 context sentence
    Summary · context
    The methods used in our experiments in old rats included determination of total antioxidant and antiradical activities, as well as those of antioxidant enzymes (superoxide dismutase=SOD, glutathione peroxidase, glutathione-S-transferase, etc.) in blood serum, liver and brain.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  2. 02AnimalNot a test of Epitalon aloneAnimal study (in vivo)Mechanism

    In old rats, epitalon and epithalamin had an antioxidant mechanism that differs from the action of melatonin.

    In plain wordsIn old rats, epitalon worked as an antioxidant by a mechanism that differs from melatonin.

    Peptide
    Epitalon
    Outcome
    Not applicableAntioxidant mechanism versus melatonin
    Study

    ratn: not reported in source

    Old rats (blood serum, liver and brain)
    Comparator
    Melatonin
    Outcome group
    Oxidative stress · Aging and longevity

    Source sentences

    Summary
    have an antioxidant mechanism that is quite different from the action of melatonin.
    1 context sentence
    Summary · context
    The methods used in our experiments in old rats included determination of total antioxidant and antiradical activities, as well as those of antioxidant enzymes (superoxide dismutase=SOD, glutathione peroxidase, glutathione-S-transferase, etc.) in blood serum, liver and brain.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

  3. 03AnimalNot a test of Epitalon aloneAnimal study (in vivo)Mechanism

    In old rats, the pineal gland peptides, including epitalon, enhanced the antioxidant defense system.

    In plain wordsIn old rats, pineal gland peptides, including epitalon, strengthened the antioxidant defense system.

    Peptide
    Epitalon
    Outcome
    IncreaseAntioxidant defense system
    Study

    ratn: not reported in source

    Old rats (blood serum, liver and brain)
    Outcome group
    Oxidative stress · Aging and longevity

    Source sentences

    Summary
    Thus, the results of our experiments testify that the pineal gland peptides enhance the antioxidant defense system, which can contribute to their geroprotective properties.
    1 context sentence
    Summary · context
    The methods used in our experiments in old rats included determination of total antioxidant and antiradical activities, as well as those of antioxidant enzymes (superoxide dismutase=SOD, glutathione peroxidase, glutathione-S-transferase, etc.) in blood serum, liver and brain.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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