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Study · Measured the body's own peptide · 2006

2 results

Insulin-like growth factor-1 isoform mRNA expression in women with endometriosis: eutopic endometrium versus endometriotic cyst.

Milingos D, Katopodis H, Milingos S, Protopapas A, Creatsas G, Michalas S, Antsaklis A, Koutsilieris M

Annals of the New York Academy of Sciences1 Dec 2006Cited by 24 (Europe PMC)

PMID17308170 (opens in a new tab)DOI10.1196/annals.1365.042 (opens in a new tab)PepBankPUB-17308170
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyMechanism

    In women with endometriosis, all three IGF-1 isoforms, including MGF (IGF-1Ec), were expressed in both eutopic endometrium and ovarian endometrioma.

    In plain wordsIn women with endometriosis, the body's own MGF was found in both the womb lining and the cyst tissue.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableIGF-1 isoform (including MGF) mRNA expression in endometrium and endometrioma
    Study

    n: not reported in source

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    We documented that all three IGF-1 isoforms are expressed in both eutopic endometrium and ovarian endometrioma.
    2 context sentences
    Summary · context
    The IGF-1 gene undergoes alternative splicing and results in three isoforms (IGF-1Ea, IGF-1Eb, and IGF-1Ec or MGF).
    Summary · context
    We analyzed the mRNA expression of IGF-1 isoforms in tissue samples of eutopic endometrium and endometriotic cyst obtained during laparoscopy from women with endometriosis.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyMechanism

    In women with endometriosis, expression of all IGF-1 isoforms, including MGF (IGF-1Ec), was significantly lower in endometriotic cyst than in endometrium.

    In plain wordsIn women with endometriosis, the body's own MGF was lower in cyst tissue than in womb lining, along with the other IGF-1 forms.

    Peptide
    MGF / PEG-MGF
    Outcome
    DecreaseIGF-1 isoform (including MGF) mRNA in endometriotic cyst versus endometrium
    Study

    n: not reported in source

    Comparator
    Eutopic endometrium
    Outcome group
    Sex hormones and fertility · Reproductive and sexual health

    Source sentences

    Summary
    Furthermore, we documented a significant decrease in all IGF-1 isoform expression in endometriotic cyst compared to endometrium of women with endometriosis.
    2 context sentences
    Summary · context
    The IGF-1 gene undergoes alternative splicing and results in three isoforms (IGF-1Ea, IGF-1Eb, and IGF-1Ec or MGF).
    Summary · context
    We analyzed the mRNA expression of IGF-1 isoforms in tissue samples of eutopic endometrium and endometriotic cyst obtained during laparoscopy from women with endometriosis.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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