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Study · Not a test of the peptide alone · 2007

2 results

Exercise training-induced remodeling of paraventricular nucleus (nor)adrenergic innervation in normotensive and hypertensive rats.

Higa-Taniguchi KT, Silva FC, Silva HM, Michelini LC, Stern JE

American journal of physiology. Regulatory, integrative and comparative physiology11 Jan 2007Cited by 40 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Oxytocin.

  1. 01AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In normotensive Wistar-Kyoto rats, exercise training increased the number and density of dopamine beta-hydroxylase boutons overlapping oxytocin neurons that project to the dorsal vagal complex.

    In plain wordsIn normotensive rats, exercise training increased nerve endings that contact oxytocin-producing brain cells.

    Peptide
    Oxytocin
    Outcome
    IncreaseNoradrenergic boutons overlapping PVN-DVC oxytocin neurons in normotensive rats
    Study

    ratn: not reported in source

    Wistar-Kyoto and spontaneously hypertensive rats with exercise training
    Comparator
    Sedentary rats
    Outcome group
    Receptor activity and mechanism · Cardiovascular

    Source sentences

    Summary
    Furthermore, the number and density of DBHir boutons overlapping PVN-DVC OTergic neurons were also increased during EXT (130%), effects that were blunted in SHR.
    1 context sentence
    Summary · context
    Confocal immunofluorescence microscopy and tract tracing were used to quantify changes in (nor)adrenergic innervation density in PVN subnuclei and in identified dorsal vagal complex (DVC) projecting neurons (PVN-DVC) in EXT normotensive [Wistar-Kyoto rat (WKY)] and hypertensive [spontaneously hypert…

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

  2. 02AnimalNot a test of Oxytocin aloneAnimal study (in vivo)Mechanism

    In spontaneously hypertensive rats, the exercise-induced increase in boutons overlapping oxytocin neurons was blunted.

    In plain wordsIn hypertensive rats, the exercise-induced increase in nerve endings on oxytocin-producing brain cells was weaker.

    Peptide
    Oxytocin
    Outcome
    MixedNoradrenergic boutons overlapping PVN-DVC oxytocin neurons in hypertensive rats
    Study

    ratn: not reported in source

    Wistar-Kyoto and spontaneously hypertensive rats with exercise training
    Outcome group
    Receptor activity and mechanism · Cardiovascular

    Source sentences

    Summary
    Furthermore, the number and density of DBHir boutons overlapping PVN-DVC OTergic neurons were also increased during EXT (130%), effects that were blunted in SHR.
    1 context sentence
    Summary · context
    Confocal immunofluorescence microscopy and tract tracing were used to quantify changes in (nor)adrenergic innervation density in PVN subnuclei and in identified dorsal vagal complex (DVC) projecting neurons (PVN-DVC) in EXT normotensive [Wistar-Kyoto rat (WKY)] and hypertensive [spontaneously hypert…

    In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 01:30 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:52 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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