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Study · Animal study (in vivo) · rat · 2006

5 results

[Efficacy of cerebrolysin in cerebral hemorrhage model in rats].

Kositsyn NS, Svinov MM, Goloborod'ko EV, Bozhevalova SV, Iablonskaia AM

Eksperimental'naia i klinicheskaia farmakologiia1 Nov 2006Cited by 1 (Europe PMC)

PMID17209460 (opens in a new tab)PepBankPUB-17209460
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with hemorrhagic stroke, Cerebrolysin reduced degenerated neurons near the hematoma during the acute period.

    In plain wordsIn rats with hemorrhagic stroke, Cerebrolysin reduced damaged neurons near the hematoma.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseDegenerated neurons in acute period
    Study

    ratn: not reported in source

    Unilateral hemorrhagic stroke
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cerebrolysin produces a neuroprotective effect, which is manifested by a decrease in the number of degenerated neurons in the vicinity of hematoma region in acute period and by a reduction of the neuronal loss in the early recovery phase.
    1 context sentence
    Summary · context
    The pharmacological efficacy of cerebrolysin (a brain-derived peptidergic drug) was studied in rats with a unilateral hemorrhagic stroke model.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats with hemorrhagic stroke, Cerebrolysin reduced neuronal loss during early recovery.

    In plain wordsIn rats with hemorrhagic stroke, Cerebrolysin reduced neuron loss during early recovery.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseNeuronal loss during early recovery
    Study

    ratn: not reported in source

    Unilateral hemorrhagic stroke
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Cerebrolysin produces a neuroprotective effect, which is manifested by a decrease in the number of degenerated neurons in the vicinity of hematoma region in acute period and by a reduction of the neuronal loss in the early recovery phase.
    1 context sentence
    Summary · context
    The pharmacological efficacy of cerebrolysin (a brain-derived peptidergic drug) was studied in rats with a unilateral hemorrhagic stroke model.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats with hemorrhagic stroke, Cerebrolysin improved functional state in neurological and behavioral tests.

    In plain wordsIn rats with hemorrhagic stroke, Cerebrolysin improved neurological and behavioral function.

    Peptide
    Cerebrolysin
    Outcome
    IncreaseNeurological and behavioral function
    Study

    ratn: not reported in source

    Unilateral hemorrhagic stroke
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Besides, the administration of cerebrolysin improves the functional state as judged from the results of neurological and behavioral tests (open field, paw licking, and passive avoidance).
    1 context sentence
    Summary · context
    The pharmacological efficacy of cerebrolysin (a brain-derived peptidergic drug) was studied in rats with a unilateral hemorrhagic stroke model.
  4. 04AnimalAnimal study (in vivo)Efficacy outcome

    In rats with hemorrhagic stroke, Cerebrolysin decreased hyperactivity in the open-field test.

    In plain wordsIn rats with hemorrhagic stroke, Cerebrolysin reduced open-field hyperactivity.

    Peptide
    Cerebrolysin
    Outcome
    DecreaseOpen-field hyperactivity
    Study

    ratn: not reported in source

    Unilateral hemorrhagic stroke
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A decrease in the hyperactivity in the open field test and the conservation of latent avoidance in the passive avoidance test demonstrate the drug influence on the maintenance of inhibitory processes deteriorated in stroke.
    1 context sentence
    Summary · context
    The pharmacological efficacy of cerebrolysin (a brain-derived peptidergic drug) was studied in rats with a unilateral hemorrhagic stroke model.
  5. 05AnimalAnimal study (in vivo)Efficacy outcome

    In rats with hemorrhagic stroke, Cerebrolysin preserved latent avoidance in the passive-avoidance test.

    In plain wordsIn rats with hemorrhagic stroke, Cerebrolysin preserved passive avoidance.

    Peptide
    Cerebrolysin
    Outcome
    IncreasePassive avoidance retention
    Study

    ratn: not reported in source

    Unilateral hemorrhagic stroke
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    A decrease in the hyperactivity in the open field test and the conservation of latent avoidance in the passive avoidance test demonstrate the drug influence on the maintenance of inhibitory processes deteriorated in stroke.
    1 context sentence
    Summary · context
    The pharmacological efficacy of cerebrolysin (a brain-derived peptidergic drug) was studied in rats with a unilateral hemorrhagic stroke model.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

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