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Study · Animal study (in vivo) · rat · 2006

1 result

[Comparative study of the effects of melatonin and epitalon on the protracted memory under the shuttle labyrinth test conditions in rats in the course of aging].

Vinogradova IA

Eksperimental'naia i klinicheskaia farmakologiia1 Nov 2006Cited by 1 (Europe PMC)

PMID17209456 (opens in a new tab)PepBankPUB-17209456
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In old rats, daily epitalon from 4 months of age decreased the extent of memory disorders in the shuttle labyrinth test.

    In plain wordsIn old rats, epitalon given daily from 4 months of age reduced memory problems in a maze test.

    Peptide
    Epitalon
    Outcome
    DecreaseMemory disorders in old rats (shuttle labyrinth test)
    Study

    ratn: not reported in source

    LIO rats aged for 2 years under 12L:12D
    Outcome group
    Cognition and memory · Nervous system and cognition
    Studied dose
    0.1 microg per animal dailyAs given in this study (rat).

    Source sentences

    Summary
    Epitalon administered in a daily dose of 0.1 microg per animal beginning with the age of 4 months showed mnemotropic properties (decreasing the extent of memory disorders) in old rats under conditions of the shuttle labyrinth test.
    1 context sentence
    Summary · context
    The influence of the chronic administration of melatonin (epiphyseal hormone) and epitalon (a synthetic tetrapeptide increasing melatonin production) on the learning process and the protracted memory has been studied in LIO rats in the course of aging for 2 years under standard illumination regime (12L :12D).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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