In dispersed bovine luteal cells, leptin increased progesterone production in the presence of IGF-1, but leptin alone had no effect.
In plain wordsIn cattle luteal cells grown in the lab, leptin raised progesterone only when IGF-1 was present, not alone.
- Peptide
- IGF-1 LR3
- Outcome
- IncreaseProgesterone production by luteal cells with leptin and IGF-1
- Study
cattlen = 14
dispersed bovine luteal cells- Comparator
- Leptin alone
- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
Measurements
- IGF-1 concentration
- 100 ng/ml
- luteal cells
- leptin concentration
- 10 ng/ml
- luteal cells
Source sentences
However, in the presence of IGF-1 (100 ng/ml), leptin (10 ng/ml) caused a significant (P<0.005) increase in progesterone production.
3 context sentences(design, population, supporting numbers)
Progesterone production by luteal cells was increased (P<0.001) by treatment with LH (10 ng/ml) but treatment with leptin alone had no effect.
The dispersed luteal cells were cultured for 24 hr with recombinant human leptin and/or LR3-IGF-1 and/or LH.
The effects of leptin on progesterone production were investigated in dispersed luteal cells prepared from CL collected on days 5 and 8 (n=14) of the cycle.
In this study, IGF-1 LR3 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking IGF-1 LR3.