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Study · Animal study (in vivo) · rat · 2006

3 results

[Effect of vilon on neuroendocrine status and sexual function of old male rats].

Kudriavtseva TA, Zaĭchenko IN, Efremov OM, Baĭramov AA, Grigor'ev EI, Ryzhak GA

Advances in gerontology = Uspekhi gerontologii1 Jan 2006

PMID17152729 (opens in a new tab)PepBankPUB-17152729
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In old male rats, regular Vilon administration activated sexual function.

    In plain wordsIn rats, regular Vilon administration increased sexual function.

    Peptide
    Vilon (KE)
    Outcome
    IncreaseSexual function
    Study

    ratn: not reported in source

    Old hemigonadectomised male rats
    Outcome group
    Sexual function · Reproductive and sexual health
    Studied dose
    50 microg per ratAs given in this study (rat).

    Source sentences

    Summary
    The results showed that regular introduction of Vilon in a dose of 50 microg per rat activates sexual function in old male rats.
    1 context sentence
    Summary · context
    The hypogonadal status of hemigonadectomised male rats has been choseh as a model of age-related sexual function decline in animals. The effect of dipeptide Vilon on parameters of sexual function and neuroendocrine status was studied.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In old male rats, Vilon affected LH and ACTH levels and hypothalamic neurotransmitter content without reported directions.

    In plain wordsIn rats, Vilon affected LH, ACTH and brain neurotransmitter levels. The abstract did not report their directions.

    Peptide
    Vilon (KE)
    Outcome
    Direction not reportedNeuroendocrine and hypothalamic neurotransmitter changes
    Study

    ratn: not reported in source

    Old hemigonadectomised male rats
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    50 microg per ratAs given in this study (rat).

    Source sentences

    Summary
    The obtained data confirm that Vilon significantly affects neuroendocrine status of animals, as well as the level of LH, prolactin and ACTH and changes the content of neurotransmitters in hypothalamus.
    1 context sentence
    Summary · context
    The hypogonadal status of hemigonadectomised male rats has been choseh as a model of age-related sexual function decline in animals. The effect of dipeptide Vilon on parameters of sexual function and neuroendocrine status was studied.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In old male rats treated with Vilon, blood prolactin content significantly decreased.

    In plain wordsIn rats, blood prolactin decreased during Vilon treatment.

    Peptide
    Vilon (KE)
    Outcome
    DecreaseBlood prolactin content
    Study

    ratn: not reported in source

    Old hemigonadectomised male rats
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    50 microg per ratAs given in this study (rat).

    Source sentences

    Summary
    Significant decrease in prolactin content in blood is worthy of notice, as age-related hypersecretion of this hormone is one of the main factors leading to age-related sexual function decline.
    2 context sentences
    Summary · context
    The obtained data confirm that Vilon significantly affects neuroendocrine status of animals, as well as the level of LH, prolactin and ACTH and changes the content of neurotransmitters in hypothalamus.
    Summary · context
    The hypogonadal status of hemigonadectomised male rats has been choseh as a model of age-related sexual function decline in animals. The effect of dipeptide Vilon on parameters of sexual function and neuroendocrine status was studied.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 17:05 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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