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Study · Animal study (in vivo) · rat · 2006

1 result

[Effect of age, different light conditions, melatonin, and epitalon on lysosomal proteinase activity in the liver and kidneys of rats].

Rendakov NL, Tiutiunnik NN, Vinogradova IA

Advances in gerontology = Uspekhi gerontologii1 Jan 2006Cited by 2 (Europe PMC)

PMID17152724 (opens in a new tab)PepBankPUB-17152724
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats, epithalon, like melatonin, decreased liver cathepsin D activity only under control interchangeable light conditions.

    In plain wordsIn rats, epithalon lowered liver cathepsin D activity, but only under normal alternating light.

    Peptide
    Epitalon
    Outcome
    DecreaseCathepsin D activity in liver
    Study

    ratn: not reported in source

    Rats of different ages under different light conditions
    Outcome group
    Aging markers · Liver
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Melatonin and epithalon administration resulted in decrease of cathepsin D activity in liver only under control interchangeable light conditions.
    1 context sentence
    Summary · context
    Ageing, melatonin, epithalon (tetrapeptide Ala-Glu-Asp-Gly) and different light conditions effects on protein content and cathepsins B and D activities in rat liver and kidneys lysosomal fractions were studied.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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