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Study · Animal study (in vivo) · rat · 2006

3 results

[Influence of light regimens, melatonin, and epitalon on amylase activity in the pancreas and small intestine in rats of different age].

Svechkina EB, Tiutiunnik NN, Vinogradova IA

Advances in gerontology = Uspekhi gerontologii1 Jan 2006Cited by 1 (Europe PMC)

PMID17152723 (opens in a new tab)PepBankPUB-17152723
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In mature rats under natural light and constant light, epitalon decreased pancreatic amylase activity, whereas melatonin increased it.

    In plain wordsIn mature rats, epitalon lowered pancreatic amylase activity, while melatonin raised it.

    Peptide
    Epitalon
    Outcome
    DecreasePancreatic amylase activity in mature rats
    Study

    ratn: not reported in source

    Rats of different ages under different light modes
    Outcome group
    Gastrointestinal function · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Melatonin use entails pancreatic amylase activity increase in mature animals in natural light of the North-West of Russia (NL) and 24-hour constant light (LD) and on the contrary amylase activity drops in case of using epitalon.
    1 context sentence
    Summary · context
    The study shows that keeping rats in different light modes has a different impact on pancreatic and intestine amylase activity and has its peculiarities in regard of age as well as geroprotectors' influence on it.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In young and old rats under constant light, amylase activity decreased with melatonin and with epitalon.

    In plain wordsIn young and old rats, amylase activity went down with epitalon and with melatonin.

    Peptide
    Epitalon
    Outcome
    DecreaseAmylase activity in young and old rats
    Study

    ratn: not reported in source

    Rats of different ages under different light modes
    Outcome group
    Gastrointestinal function · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Simultaneously, the enzyme activity in young and old rats under LD, melatonin and epitalon decreases.
    1 context sentence
    Summary · context
    The study shows that keeping rats in different light modes has a different impact on pancreatic and intestine amylase activity and has its peculiarities in regard of age as well as geroprotectors' influence on it.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    Intestinal amylase activity, under epitalon and melatonin, rose in natural light and dropped in constant light compared with controls.

    In plain wordsIn rats, intestinal amylase activity rose or fell with epitalon and melatonin depending on the light mode.

    Peptide
    Epitalon
    Outcome
    MixedIntestinal amylase activity
    Study

    ratn: not reported in source

    Rats of different ages under different light modes
    Outcome group
    Gastrointestinal function · Gastrointestinal
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Intestine amylase activity influenced by both preparations rises in NL and drops in LD mode with respect to the control group.
    1 context sentence
    Summary · context
    The study shows that keeping rats in different light modes has a different impact on pancreatic and intestine amylase activity and has its peculiarities in regard of age as well as geroprotectors' influence on it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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