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Study · Animal study (in vivo) · rat · 2006

3 results

Interleukin-2 concentration in hypothalamic structures of rats receiving peptides during mild stress.

Barabanova SV, Artyukhina ZE, Kazakova TB, Khavinson VKh, Malinin VV, Korneva EA

Bulletin of experimental biology and medicine1 Apr 2006Cited by 2 (Europe PMC)

PMID17152351 (opens in a new tab)DOI10.1007/s10517-006-0179-z (opens in a new tab)PepBankPUB-17152351
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In rats under mild stress, the number of IL-2-positive cells in hypothalamic structures decreased 24 h after intramuscular injection of Epithalon.

    In plain wordsIn rats under mild stress, Epithalon injected into muscle lowered the number of IL-2-positive cells in brain hypothalamus regions after 24 hours.

    Peptide
    Epitalon
    Outcome
    DecreaseIL-2-positive cells in hypothalamic structures after intramuscular Epithalon
    Study

    ratn: not reported in source

    Rats during mild stress (handling)
    Outcome group
    Inflammation markers · Nervous system and cognition
    Studied dose
    Dose not stated · intramuscularAs given in this study (rat).

    Source sentences

    Summary
    The number of IL-2-positive cells in hypothalamic structures decreased 24 h after intramuscular injection of Epithalon
  2. 02AnimalAnimal study (in vivo)Mechanism

    In rats adapted to experimental conditions, intranasal Epithalon did not decrease the number of IL-2-positive cells in the supraoptic nucleus.

    In plain wordsIn rats adapted to the experiment, nasal Epithalon did not lower the number of IL-2-positive cells in the supraoptic nucleus.

    Peptide
    Epitalon
    Outcome
    No significant changeIL-2-positive cells in supraoptic nucleus after adaptation
    Study

    ratn: not reported in source

    Rats during mild stress (handling)
    Outcome group
    Inflammation markers · Nervous system and cognition
    Studied dose
    Dose not stated · intranasalAs given in this study (rat).

    Source sentences

    Summary
    Adaptation of animals to experimental conditions prevented the decrease in the number of IL-2-positive cells in the supraoptic nucleus after intranasal administration of Epithalon.

Studies that did not test the peptide alone1

In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Epitalon.

  1. 03AnimalNot a test of Epitalon aloneAnimal study (in vivo)Mechanism

    In rats under mild stress, the number of IL-2-positive cells in hypothalamic structures decreased 2 h after intranasal administration of the test peptides (Vilon and Epithalon).

    In plain wordsIn rats under mild stress, nasal Vilon and Epithalon together lowered the number of IL-2-positive cells in hypothalamus regions after 2 hours.

    Peptide
    Epitalon
    Outcome
    DecreaseIL-2-positive cells in hypothalamic structures after intranasal peptides
    Study

    ratn: not reported in source

    Rats during mild stress (handling)
    Outcome group
    Inflammation markers · Nervous system and cognition

    Source sentences

    Summary
    and 2 h after intranasal administration of the test peptides.

    In this study, Epitalon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Epitalon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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