In men with early parental separation, intranasal oxytocin led to attenuated cortisol decreases compared with control men, relative to placebo.
In plain wordsIn men who lost a parent early, oxytocin lowered cortisol less than in control men, relative to placebo.
- Peptide
- Oxytocin
- Outcome
- MixedSalivary cortisol response to intranasal oxytocin
- Study
n = 19
- Comparator
- Placebo condition; control men without early parental separation
- Outcome group
- Stress hormones · Endocrine and hormones
- Studied dose
- 24 IU · intranasalAs given in this study (human).
Source sentences
Relative to placebo, intranasal OT resulted in attenuated cortisol decreases in EPS subjects compared with control subjects.
1 context sentence(design, population, supporting numbers)
Salivary cortisol concentrations were measured in 9 healthy men with EPS and 10 control subjects before and after double-blind intranasal administration of placebo and OT (24 IU Syntocinon).