Correction of cerebral ischemia in low-resistant animals with an antistress drug Deltaran.

Gannushkina IV, Konorova IL, Koplik EV, Antelava AL

Bulletin of experimental biology and medicine1 Mar 2006

PMID17073141DOI10.1007/s10517-006-0152-xPepBankPUB-17073141

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study6

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone6

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

01AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In ischemia-sensitive Wistar rats after carotid artery occlusion, Deltaran decreased the amplitude of EEG slow waves.
In plain wordsIn rats with brain ischemia, the drug Deltaran lowered the size of slow brain waves.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseEEG slow-wave amplitude
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
Deltaran decreased the amplitude of EEG slow waves
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314101
02AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In ischemia-sensitive Wistar rats after carotid artery occlusion, Deltaran restored neuronal reactivity.
In plain wordsIn rats with brain ischemia, the drug Deltaran restored the response of brain cells.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
IncreaseNeuronal reactivity
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314102
03AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In rats with cerebral ischemia, Deltaran had no effect on local cerebral blood flow.
In plain wordsIn rats with brain ischemia, the drug Deltaran did not change local blood flow in the brain.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
No significant changeLocal cerebral blood flow
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
Deltaran had no effect on local cerebral blood flow.
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314103
04AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In intact rats during the acute stage of cerebral ischemia, Deltaran increased blood supply to a unit of neuronal activity.
In plain wordsIn rats in the early stage of brain ischemia, the drug Deltaran raised blood supply for each unit of brain activity.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
IncreaseBlood supply per unit of neuronal activity
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
increased blood supply to a unit of neuronal activity in the brain of intact animals during the acute stage of cerebral ischemia
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314104
05AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In rats with cerebral ischemia, Deltaran gave a 100% survival rate.
In plain wordsIn rats with brain ischemia, all rats given the drug Deltaran survived.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
IncreaseSurvival
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Mortality · Nervous system and cognition
Measurements
Survival rate
100%
Deltaran, rats with cerebral ischemia
Source sentences
Summary
provided 100% survival rate of rats with cerebral ischemia
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314105
06AnimalNot a test of Delta sleep-inducing peptide (DSIP) aloneAnimal study (in vivo)Efficacy outcome
In surviving rats with cerebral ischemia, Deltaran prevented the development of neurological symptoms.
In plain wordsIn rats with brain ischemia, the drug Deltaran prevented nerve-related symptoms in the survivors.
Peptide
Delta sleep-inducing peptide (DSIP)
Outcome
DecreaseNeurological symptoms in survivors
Study
ratn: not reported in source
cerebral ischemia after carotid artery occlusion in ischemia-sensitive Wistar rats
Outcome group
Neuroprotection · Nervous system and cognition
Source sentences
Summary
prevented the development of neurological symptoms in survivors.
1 context sentence(design, population, supporting numbers)
Summary · context
Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia.
In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).
Report a problemFND-1707314106

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
10 Oct 2026, 08:55 UTC
Study results updated
Version 1
9 Oct 2026, 12:40 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

Journal Article

MeSH terms

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