In cultured porcine embryonic myogenic cells, IGFBP-3 had no effect on Long-R3-IGF-I-stimulated differentiation, while it suppressed IGF-I-stimulated differentiation.
In plain wordsIn pig muscle cells grown in the lab, IGFBP-3 did not change differentiation driven by Long-R3-IGF-I.
- Peptide
- IGF-1 LR3
- Outcome
- No significant changeIGFBP-3 effect on Long-R3-IGF-I-stimulated differentiation
- Study
pign: not reported in source
cultured porcine embryonic myogenic cells- Comparator
- IGF-I-stimulated differentiation
- Outcome group
- Receptor activity and mechanism · Musculoskeletal
Source sentences
IGFBP-3 suppresses IGF-I-stimulated differentiation of PEMC but has no affect on Long-R3-IGF-I-stimulated differentiation of PEMC.
1 context sentence(design, population, supporting numbers)
IGFBP-3 is produced by porcine embryonic myogenic cell (PEMC) cultures.
In this study, IGF-1 LR3 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking IGF-1 LR3.