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Study · Not a test of the peptide alone · 2006

3 results

Monoclonal antibodies to mechano-growth factor.

Kravchenko IV, Furalyov VA, Khotchenkov VP, Popov VO

Hybridoma (2005)1 Oct 2006Cited by 13 (Europe PMC)

PMID17044786 (opens in a new tab)DOI10.1089/hyb.2006.25.300 (opens in a new tab)PepBankPUB-17044786
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking MGF / PEG-MGF.

  1. 01LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Activity measurement

    Monoclonal antibodies of clone 8B9 recognized a human MGF peptide of amino acids 87 to 111 that is absent in IGF-1.

    In plain wordsIn lab tests, antibodies of one clone bound a part of human MGF that IGF-1 does not have.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableAntibody 8B9 epitope on human MGF
    Study

    n: not reported in source

    monoclonal antibodies tested by ELISA
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    MAbs of one clone (8B9) recognize human MGF peptide absent in insulin-like growth factor-1 (IGF-1) and comprising amino acids from 87 to 111.
    1 context sentence
    Summary · context
    Two hybridoma clones secreting monoclonal antibodies (MAbs) to mechano-growth factor (MGF) have been produced by cell fusion technique.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  2. 02LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Activity measurement

    No competition was detected between the two monoclonal antibodies, so they recognize different antigenic determinants of MGF.

    In plain wordsIn lab tests, the two antibodies did not compete, so they bind different parts of MGF.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableEpitope specificity of two MGF antibodies
    Study

    n: not reported in source

    monoclonal antibodies tested by ELISA
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    The epitope specificity of the MAbs has been examined in competition experiments. No competition was detected, suggesting that the MAbs obtained recognize different antigenic determinants.
    1 context sentence
    Summary · context
    Two hybridoma clones secreting monoclonal antibodies (MAbs) to mechano-growth factor (MGF) have been produced by cell fusion technique.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

  3. 03LabNot a test of MGF / PEG-MGF aloneIn vitro (cell-free)Activity measurement

    A pair of the monoclonal antibodies can be used in a sandwich-type assay to quantify MGF.

    In plain wordsIn lab tests, a pair of these antibodies can measure MGF in a sandwich assay.

    Peptide
    MGF / PEG-MGF
    Outcome
    Not applicableSandwich assay to quantify MGF
    Study

    n: not reported in source

    monoclonal antibodies tested by ELISA
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    A pair of monoclonal antibodies obtained can be used in a sandwich-type assay to quantify MGF.
    1 context sentence
    Summary · context
    Two hybridoma clones secreting monoclonal antibodies (MAbs) to mechano-growth factor (MGF) have been produced by cell fusion technique.

    In this study, MGF / PEG-MGF was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking MGF / PEG-MGF.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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