In rats, hypophysectomy caused substantial degeneration of oxytocin neurons in the supraoptic and paraventricular nuclei in both immature and adult rats, with no obvious difference in neuronal survival among the three age groups.
In plain wordsIn rats, removing the pituitary caused loss of oxytocin nerve cells at all ages tested.
- Peptide
- Oxytocin
- Outcome
- DecreaseOxytocin neuron survival after hypophysectomy
- Study
ratn: not reported in source
- Outcome group
- Neuroprotection · Endocrine and hormones
Source sentences
hypophysectomy induced substantial degeneration of arginine vasopressin (AVP) and oxytocin (OT) neurons in the SON and PVN in both immature and adult rats and there was no obvious difference in neuronal survival after the same injury among these three groups of different ages by quantitative analysis
1 context sentence(design, population, supporting numbers)
This study examined the age-related changes in nitric oxide synthase immunoreactivity (NOS-IR), survival and regeneration of magnocellular neurons in the hypothalamo-neurohypophyseal system (HNS) in rats following hypophysectomy.
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.