In osteoblasts, cyclic stretching had a more significant effect on MGF mRNA expression than other conditions, while unstrained cells did not express MGF.
In plain wordsIn cells, stretching raised the cells' own MGF messenger RNA. Cells without stretch did not make it.
- Peptide
- MGF / PEG-MGF
- Outcome
- IncreaseMGF mRNA expression with cyclic stretching
- Study
n: not reported in source
osteoblasts under static and cyclic stretching- Comparator
- Unstrained cells
- Outcome group
- Bone and joint · Musculoskeletal
Source sentences
Cyclic-stretching had a more significant effect on cell proliferation and mRNA expression levels of IGF-I and MGF, while unstrained cells did not express MGF at the mRNA level.
2 context sentences(design, population, supporting numbers)
Cell proliferation and mRNA expression of insulin-like growth factor (IGF-I) and "mechanogrowth factor" (MGF) were studied in osteoblasts in response to overload.
Static and cyclic-stretching were used to apply superphysiological strains to cells.
This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.