In adults with autism or Asperger's disorder, those who received intravenous oxytocin first kept their affective speech comprehension after a delay, while those who received placebo first tended to revert to baseline.
In plain wordsIn adults with autism, those given oxytocin first kept their improved reading of emotion in speech after a delay; placebo-first adults slipped back.
- Peptide
- Oxytocin
- Outcome
- IncreaseRetention of affective speech comprehension
- Study
n = 15
- Comparator
- Placebo
- Outcome group
- Cognition and memory · Nervous system and cognition
- Studied dose
- Dose not stated · intravenousAs given in this study (human).
Source sentences
All subjects showed improvements in affective speech comprehension from pre- to post-infusion; however, whereas those who received placebo first tended to revert to baseline after a delay, those who received oxytocin first retained the ability to accurately assign emotional significance to speech in…
1 context sentence(design, population, supporting numbers)
Oxytocin and placebo challenges were administered to 15 adult subjects diagnosed with autism or Asperger's disorder, and comprehension of affective speech (happy, indifferent, angry, and sad) in neutral content sentences was tested.