Skip to content

Study · In vitro (cells) · 2006

3 results

NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function.

Quintana FJ, Zaltzman R, Fernandez-Montesinos R, Herrera JL, Gozes I, Cohen IR, Pozo D

Annals of the New York Academy of Sciences1 Jul 2006Cited by 35 (Europe PMC)

PMID16888216 (opens in a new tab)DOI10.1196/annals.1317.069 (opens in a new tab)PepBankPUB-16888216
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Mechanism

    In macrophages, NAP downregulated TNF-alpha.

    In plain wordsIn cells, NAP reduced the inflammatory cytokine TNF-alpha.

    Peptide
    Davunetide
    Outcome
    DecreaseTNF-alpha
    Study

    n: not reported in source

    Macrophages
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    (c) NAP downregulates the key inflammatory cytokines tumor necrosis factor (TNF-alpha), interleukin-16 (IL-16), and IL-12 in macrophages.
  2. 02LabIn vitro (cells)Mechanism

    In macrophages, NAP downregulated IL-16.

    In plain wordsIn cells, NAP reduced the inflammatory cytokine IL-16.

    Peptide
    Davunetide
    Outcome
    DecreaseIL-16
    Study

    n: not reported in source

    Macrophages
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    (c) NAP downregulates the key inflammatory cytokines tumor necrosis factor (TNF-alpha), interleukin-16 (IL-16), and IL-12 in macrophages.
  3. 03LabIn vitro (cells)Mechanism

    In macrophages, NAP downregulated IL-12.

    In plain wordsIn cells, NAP reduced the inflammatory cytokine IL-12.

    Peptide
    Davunetide
    Outcome
    DecreaseIL-12
    Study

    n: not reported in source

    Macrophages
    Outcome group
    Inflammation markers · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    (c) NAP downregulates the key inflammatory cytokines tumor necrosis factor (TNF-alpha), interleukin-16 (IL-16), and IL-12 in macrophages.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    27 Oct 2026, 18:20 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:32 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.