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Study · Measured the body's own peptide · 2006

2 results

Effects of Morris water maze testing on the neuroendocrine stress response and intrahypothalamic release of vasopressin and oxytocin in the rat.

Engelmann M, Ebner K, Landgraf R, Wotjak CT

Hormones and behavior27 Jul 2006Cited by 65 (Europe PMC)

PMID16875693 (opens in a new tab)DOI10.1016/j.yhbeh.2006.04.009 (opens in a new tab)PepBankPUB-16875693
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In male rats, swimming in the Morris water maze significantly increased the release of the body's own oxytocin within the supraoptic nucleus on each of the 3 test sessions.

    In plain wordsIn rats, swimming in a water maze raised the release of the body's own oxytocin in one brain area.

    Peptide
    Oxytocin
    Outcome
    IncreaseOxytocin release in the supraoptic nucleus during Morris water maze swimming
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    swimming in the MWM caused a significantly increased release of AVP within the PVN and of OXT within the SON on each of the 3 test sessions.
    1 context sentence
    Summary · context
    Adult male Wistar rats were trained in the Morris water maze (MWM) on 3 consecutive days to find a visible platform.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In male rats, basal oxytocin concentrations in the supraoptic nucleus did not rise from day to day, unlike basal vasopressin in the paraventricular nucleus.

    In plain wordsIn rats, the resting level of the body's own oxytocin in one brain area did not rise from day to day.

    Peptide
    Oxytocin
    Outcome
    No significant changeBasal oxytocin concentration in the supraoptic nucleus across days
    Study

    ratn: not reported in source

    Outcome group
    Endogenous peptide levels · Endocrine and hormones

    Source sentences

    Summary
    In contrast to OXT in the SON, basal AVP concentrations in the PVN tended to rise from day to day.
    1 context sentence
    Summary · context
    Adult male Wistar rats were trained in the Morris water maze (MWM) on 3 consecutive days to find a visible platform.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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