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Study · Randomized controlled trial · n = 13 · 2006

4 results

Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin.

Miller TR, Wagner JD, Baack BR, Eisbach KJ

Archives of facial plastic surgery1 Jul 2006Cited by 6 (Europe PMC)

PMID16847171 (opens in a new tab)DOI10.1001/archfaci.8.4.252 (opens in a new tab)PepBankPUB-16847171
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients after CO2 laser skin resurfacing, topical GHK‑Cu did not give earlier resolution of erythema than a regimen without GHK‑Cu.

    In plain wordsIn patients after laser skin resurfacing, skin care with GHK‑Cu did not clear redness earlier than care without it.

    Peptide
    GHK-Cu
    Outcome
    No significant changeErythema resolution after CO2 laser resurfacing
    Study

    n = 13

    Comparator
    Skin regimen without GHK-Cu
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated · topicalAs given in this study (human).

    Source sentences

    Summary
    Computer analysis and blinded evaluators found no statistically significant differences between groups for earlier resolution of erythema.
    2 context sentences
    Summary · context
    Patients meeting the inclusion criteria underwent circumoral skin resurfacing using a CO(2) laser at standard settings.
    Summary · context
    Patients were then randomized to receive posttreatment skin regimens with or without GHK-Cu.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients after CO2 laser skin resurfacing, all patients improved in wrinkles, with no difference between the GHK‑Cu and no-GHK‑Cu groups.

    In plain wordsIn patients after laser resurfacing, wrinkles improved in all patients, with no difference between groups with and without GHK‑Cu.

    Peptide
    GHK-Cu
    Outcome
    No significant changeImprovement in wrinkles
    Study

    n = 13

    Comparator
    Skin regimen without GHK-Cu
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated · topicalAs given in this study (human).

    Source sentences

    Summary
    All the patients experienced significant improvement in wrinkles and overall skin quality, but no differences were found between groups.
    2 context sentences
    Summary · context
    Patients meeting the inclusion criteria underwent circumoral skin resurfacing using a CO(2) laser at standard settings.
    Summary · context
    Patients were then randomized to receive posttreatment skin regimens with or without GHK-Cu.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In patients after CO2 laser skin resurfacing, overall skin quality improved in all patients, with no difference between the GHK‑Cu and no-GHK‑Cu groups.

    In plain wordsIn patients after laser resurfacing, overall skin quality improved in all patients, with no difference between groups with and without GHK‑Cu.

    Peptide
    GHK-Cu
    Outcome
    No significant changeImprovement in overall skin quality
    Study

    n = 13

    Comparator
    Skin regimen without GHK-Cu
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated · topicalAs given in this study (human).

    Source sentences

    Summary
    All the patients experienced significant improvement in wrinkles and overall skin quality, but no differences were found between groups.
    2 context sentences
    Summary · context
    Patients meeting the inclusion criteria underwent circumoral skin resurfacing using a CO(2) laser at standard settings.
    Summary · context
    Patients were then randomized to receive posttreatment skin regimens with or without GHK-Cu.
  4. 04HumanRandomized controlled trialEfficacy outcome

    In patients after CO2 laser skin resurfacing, the questionnaire showed a significantly greater improvement in overall skin quality for patients using GHK‑Cu.

    In plain wordsIn patients after laser resurfacing, those using GHK‑Cu products reported a larger improvement in overall skin quality on a questionnaire.

    Peptide
    GHK-Cu
    Outcome
    IncreasePatient-reported improvement in overall skin quality
    Study

    n = 13

    Comparator
    Skin regimen without GHK-Cu
    Outcome group
    Skin and hair · Skin and wound
    Studied dose
    Dose not stated · topicalAs given in this study (human).

    Source sentences

    Summary
    The results of the questionnaire indicated a significant difference in the posttreatment improvement of overall skin quality for patients using GHK-Cu (P = .04).
    2 context sentences
    Summary · context
    Patients meeting the inclusion criteria underwent circumoral skin resurfacing using a CO(2) laser at standard settings.
    Summary · context
    Patients were then randomized to receive posttreatment skin regimens with or without GHK-Cu.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:56 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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