In men receiving androgen deprivation therapy, leuprolide alone was linked to significant increases in total cholesterol, triglycerides, and HDL cholesterol.
In plain wordsIn men receiving androgen deprivation therapy, leuprolide alone was linked to higher total cholesterol, triglycerides, and HDL cholesterol.
- Peptide
- Leuprolide
- Outcome
- IncreaseTotal cholesterol, triglycerides, and HDL cholesterol
- Study
n: not reported in source
- Analysis
- Exploratory
- Outcome group
- Lipids · Metabolic and weight
- Studied dose
- Dose not stated
Source sentences
Significant increases in total cholesterol, triglyceride and high density lipoprotein-cholesterol were observed in patients on leuprolide acetate or abarelix but not in patients on leuprolide acetate plus bicalutamide.
2 context sentences(design, population, supporting numbers)
Most patients were treated in the neoadjuvant setting or because of biochemical recurrence.
In the current study men were categorized into 3 treatment groups according to the type of androgen deprivation therapy, that is leuprolide acetate, leuprolide acetate plus bicalutamide or abarelix, and statin therapy.