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Study · Not a test of the peptide alone · 2006

3 results

[Arachidonoyl amino acids and arachidonoyl peptides: synthesis and properties].

Bezuglov VV, Gretskaia NM, Blazhenova AV, Adrianova EL, Akimov AV, Bobrov MIu, Nazimov IV, Kisel' MI, Sharko OL, Novikov AV, Krasnov NV, Shevchenko VP, V'iunova TV, Miasoedova NF

Bioorganicheskaia khimiia1 May 2006Cited by 7 (Europe PMC)

PMID16808168 (opens in a new tab)DOI10.1134/s1068162006030046 (opens in a new tab)PepBankPUB-16808168
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Semax was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Semax.

  1. 01LabNot a test of Semax aloneIn vitro (cell-free)Activity measurement

    N-acylation of Semax with arachidonic acid enhanced its hydrolytic stability in lab tests.

    In plain wordsIn lab tests, attaching arachidonic acid to Semax made it more stable against breakdown by hydrolysis.

    Peptide
    Semax
    Outcome
    IncreaseHydrolytic stability of arachidonoyl-Semax
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    N-acylation of Semax with arachidonic acid results in enhancement of its hydrolytic stability and increases its affinity for the sites of specific binding in rat cerebellum membranes.

    In this study, Semax was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semax.

  2. 02LabNot a test of Semax aloneIn vitro (cell-free)Activity measurement

    N-acylation of Semax with arachidonic acid increased its affinity for specific binding sites in rat cerebellum membranes.

    In plain wordsIn lab tests with rat brain membranes, attaching arachidonic acid to Semax raised its affinity for binding sites.

    Peptide
    Semax
    Outcome
    IncreaseBinding affinity of arachidonoyl-Semax in rat cerebellum membranes
    Study

    ratn: not reported in source

    Rat cerebellum membranes
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    increases its affinity for the sites of specific binding in rat cerebellum membranes.
    1 context sentence
    Summary · context
    N-acylation of Semax with arachidonic acid

    In this study, Semax was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semax.

  3. 03LabNot a test of Semax aloneIn vitro (cell-free)Other

    Electrospray mass spectrometry detected the synthesized arachidonoyl amino acids and peptides, including those of Semax, down to 10 fmol per sample.

    In plain wordsIn lab tests, mass spectrometry detected the synthesized arachidonoyl compounds, including Semax compounds, at amounts as low as 10 fmol per sample.

    Peptide
    Semax
    Outcome
    Not applicableMass spectrometric detection limit of arachidonoyl compounds
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Detection limit
    10 fmol
    per sample

    Source sentences

    Summary
    The mass spectra of all the compounds at atmospheric pressure electrospray ionization display the most intense peaks of protonated molecular ions; the detection limits for these compounds are 10 fmol per sample.
    1 context sentence
    Summary · context
    N-Arachidonoyl (AA) derivatives of amino acids (glycine, phenylalanine, proline, valine, gamma-amino butyric acid (GABA), dihydroxyphenylalanine, tyrosine, tryptophan, and alanine) and peptides (Semax, MEHFPGP, and PGP) were synthesized in order to study the biological properties of acylamino acids.

    In this study, Semax was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Semax.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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