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Study · Measured the body's own peptide · 2006

1 result

Expression of insulin-like growth factor I, insulin-like growth factor binding proteins, and collagen mRNA in mechanically loaded plantaris tendon.

Olesen JL, Heinemeier KM, Haddad F, Langberg H, Flyvbjerg A, Kjaer M, Baldwin KM

Journal of applied physiology (Bethesda, Md. : 1985)1 Jul 2006Cited by 91 (Europe PMC)

PMID16782835 (opens in a new tab)DOI10.1152/japplphysiol.00636.2005 (opens in a new tab)PepBankPUB-16782835
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, MGF was expressed and upregulated in mechanically loaded plantaris tendon, with a faster response than IGF-I.

    In plain wordsIn rats, the body's own MGF rose in loaded tendon, earlier than IGF-I.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF expression in mechanically loaded tendon
    Study

    ratn: not reported in source

    plantaris tendon after synergist muscle removal
    Outcome group
    Tendon and ligament healing · Musculoskeletal

    Source sentences

    Summary
    MGF was expressed and upregulated in loaded tendon tissue with a faster response than IGF-I, which was increased from day 8.
    2 context sentences
    Summary · context
    This study examined the effect of mechanical load on tendon collagen mRNA in relation to changes in the IGF-I systems mRNA expression.
    Summary · context
    Data were collected at 2, 4, 8 and 16 days after surgical removal of synergistic muscle to the plantaris muscle of the rat, thus increasing the load to plantaris muscle and tendon.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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