Skip to content

Study · Animal study (in vivo) · rat · 2005

3 results

Effect of delta-sleep-inducing peptide on activity of enzymes of biogenic amine metabolism in the brain of Wistar and August rats.

Dovedova EL, Khrustalev DA, Khudoerkov RM

Bulletin of experimental biology and medicine1 Nov 2005Cited by 2 (Europe PMC)

PMID16758612 (opens in a new tab)DOI10.1007/s10517-006-0011-9 (opens in a new tab)PepBankPUB-16758612
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In Wistar and August rats, short-term DSIP exposure activated the serotonin-metabolizing enzyme system in the brain.

    In plain wordsIn rats, DSIP raised the activity of the brain's serotonin system.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    IncreaseSerotonergic system enzyme activity
    Study

    ratn: not reported in source

    Wistar and August rats, brain enzyme activity
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    activation of the serotoninergic system
    1 context sentence
    Summary · context
    Activity of enzymes catalyzing synthesis and degradation of serotonin and dopamine in brain structures of Wistar and August rats was measured biochemically under normal conditions and after short-term exposure to delta-sleep-inducing peptide.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In Wistar and August rats, short-term DSIP exposure inhibited the dopamine-metabolizing enzyme system, particularly in the caudate nucleus.

    In plain wordsIn rats, DSIP lowered the activity of the brain's dopamine system, most in the caudate nucleus.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    DecreaseDopaminergic system enzyme activity
    Study

    ratn: not reported in source

    Wistar and August rats, brain enzyme activity
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    inhibition of the dopaminergic system, particularly in the caudate nucleus.
    1 context sentence
    Summary · context
    Activity of enzymes catalyzing synthesis and degradation of serotonin and dopamine in brain structures of Wistar and August rats was measured biochemically under normal conditions and after short-term exposure to delta-sleep-inducing peptide.
  3. 03AnimalAnimal study (in vivo)Mechanism

    The DSIP-induced enzyme changes were most pronounced in the brain of Wistar rats compared with August rats.

    In plain wordsIn rats, DSIP changed brain enzyme activity most in Wistar rats.

    Peptide
    Delta sleep-inducing peptide (DSIP)
    Outcome
    Not applicableStrain difference in enzyme effects
    Study

    ratn: not reported in source

    Wistar and August rats, brain enzyme activity
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated

    Source sentences

    Summary
    These changes were most pronounced in the brain of Wistar rats.
    1 context sentence
    Summary · context
    Activity of enzymes catalyzing synthesis and degradation of serotonin and dopamine in brain structures of Wistar and August rats was measured biochemically under normal conditions and after short-term exposure to delta-sleep-inducing peptide.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.