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Study · Measured the body's own peptide · 2006

2 results

Kainic acid activates oxytocinergic neurons through non-nmda glutamate receptors.

Zehra Minbay F, Eyigor O, Cavusoglu I

The International journal of neuroscience1 May 2006Cited by 6 (Europe PMC)

PMID16644519 (opens in a new tab)DOI10.1080/00207450600592123 (opens in a new tab)PepBankPUB-16644519
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, kainic acid significantly increased c-Fos expression in oxytocin neurons of the supraoptic and paraventricular nuclei compared with controls.

    In plain wordsIn rats, kainic acid switched on more of the brain cells that make the body's own oxytocin than in controls.

    Peptide
    Oxytocin
    Outcome
    Increasec-Fos expression in oxytocin neurons after kainic acid
    Study

    ratn: not reported in source

    in vivo, SON and PVN
    Comparator
    Control group
    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    Dual immunohistochemistry for oxytocin and c-Fos showed that oxytocin neurons in SON and PVN express c-Fos following kainic acid administration, a significant increase when compared to the control group.
    1 context sentence
    Summary · context
    The present study assessed if kainic acid activates oxytocinergic neurons and this activation is blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, CNQX given before kainic acid significantly reduced the c-Fos activation of oxytocin neurons.

    In plain wordsIn rats, a blocking drug reduced the kainic acid activation of the brain cells that make the body's own oxytocin.

    Peptide
    Oxytocin
    Outcome
    Decreasec-Fos expression in oxytocin neurons after CNQX plus kainic acid
    Study

    ratn: not reported in source

    in vivo, SON and PVN
    Comparator
    Kainic acid alone
    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    Administration of CNQX prior to kainic acid caused a significant reduction.
    1 context sentence
    Summary · context
    The present study assessed if kainic acid activates oxytocinergic neurons and this activation is blocked by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX).

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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