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Study · Measured the body's own peptide · 2006

2 results

Quantification of neuropeptides (calcitonin gene-related peptide, substance P, neurokinin A, neuropeptide Y and vasoactive intestinal polypeptide) expressed in healthy and inflamed human dental pulp.

Caviedes-Bucheli J, Lombana N, Azuero-Holguín MM, Munoz HR

International endodontic journal1 May 2006Cited by 63 (Europe PMC)

PMID16640639 (opens in a new tab)DOI10.1111/j.1365-2591.2006.01093.x (opens in a new tab)PepBankPUB-16640639
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In human dental pulp, the body's own VIP expression remained stable in inflamed pulp compared with healthy pulp.

    In plain wordsIn human teeth, the body's own VIP levels did not rise in inflamed pulp compared with healthy pulp.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    No significant changeVIP expression in inflamed dental pulp
    Study

    n = 18

    Human dental pulp samples
    Comparator
    Healthy pulp
    Outcome group
    Inflammation markers · Immune and inflammation

    Source sentences

    Summary
    VIP expression remained stable during the inflammatory conditions.
    2 context sentences
    Summary · context
    Six pulp samples were obtained from teeth having a clinical diagnosis of acute irreversible pulpitis.
    Summary · context
    Another 12 pulp samples were obtained from premolars where extraction was indicated for orthodontic purposes.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelObservational studyOther

    In human dental pulp, VIP expression was found in all samples.

    In plain wordsThe body's own VIP was found in every human dental pulp sample tested.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    Not applicableVIP expression detected in dental pulp
    Study

    n = 18

    Human dental pulp samples
    Outcome group
    Inflammation markers · Immune and inflammation

    Source sentences

    Summary
    Expression of five neuropeptides was found in all human pulp samples.
    2 context sentences
    Summary · context
    Six pulp samples were obtained from teeth having a clinical diagnosis of acute irreversible pulpitis.
    Summary · context
    Another 12 pulp samples were obtained from premolars where extraction was indicated for orthodontic purposes.

    This result measures the body's own Vasoactive intestinal peptide (VIP, aviptadil). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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