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Study · Not a test of the peptide alone · 2006

1 result

Melanocortin 4 receptors interact with antimicrobial frog peptide analogues.

Do EU, Jo EB, Choi G, Piao LZ, Shin J, Seo MD, Kang SJ, Lee BJ, Kim KH, Kim JB, Kim SI

Biochemical and biophysical research communications23 Mar 2006Cited by 6 (Europe PMC)

PMID16579969 (opens in a new tab)DOI10.1016/j.bbrc.2006.03.082 (opens in a new tab)PepBankPUB-16579969
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan II.

  1. 01LabNot a test of Melanotan II aloneOther designActivity measurement

    In a human MC4R fluorescence polarization assay, the potency rank order of reference ligands was SHU9119>MTII>NDP alphaMSH>alphaMSH, in line with published assays.

    In plain wordsIn lab tests, an MC4R binding assay ranked MTII as more potent than NDP-alphaMSH and alphaMSH, as in earlier assays.

    Peptide
    Melanotan II
    Outcome
    Not applicableRank order of potency of reference ligands in MC4R fluorescence polarization assay
    Study

    n: not reported in source

    MC4R fluorescence polarization assay
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    The rank order of potency of agonists and antagonists agrees well relative to the published assays: SHU9119>MTII>NDP alphaMSH>alphaMSH.
    1 context sentence
    Summary · context
    We have developed fluorescence polarization (FP) assays of human melanocortin 4 receptor (MC4R) in 384-well microtiter plates using TAMRA-NDP-MSH as a tracer.

    In this study, Melanotan II was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan II.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    10 Oct 2026, 09:43 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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