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Study · Measured the body's own peptide · 2006

2 results

Aging-sensitive cellular and molecular mechanisms associated with skeletal muscle hypertrophy.

Haddad F, Adams GR

Journal of applied physiology (Bethesda, Md. : 1985)22 Dec 2005Cited by 109 (Europe PMC)

PMID16373446 (opens in a new tab)DOI10.1152/japplphysiol.01227.2005 (opens in a new tab)PepBankPUB-16373446
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In young and old rats, resistance exercise increased muscle mechano-growth factor mRNA.

    In plain wordsIn rats, resistance exercise raised the body's own mechano-growth factor levels in muscle.

    Peptide
    MGF / PEG-MGF
    Outcome
    IncreaseMGF mRNA after resistance exercise
    Study

    ratn: not reported in source

    6- and 30-month-old rats, resistance exercise
    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    RE induced increases in the mRNAs for IGF-I, mechano-growth factor, cyclin D1, and suppressor of cytokine signaling 3 were similar in old and young muscles.
    1 context sentence
    Summary · context
    Comparing 6- and 30-mo-old rats, the aims were to 1) determine whether these markers are altered with age and 2) identify age-sensitive responses to acute RE.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In rats, the exercise-induced rise in mechano-growth factor mRNA was similar in old and young muscles.

    In plain wordsIn rats, the body's own mechano-growth factor rose after exercise by a similar amount in old and young muscle.

    Peptide
    MGF / PEG-MGF
    Outcome
    No significant changeMGF mRNA response to resistance exercise, old versus young
    Study

    ratn: not reported in source

    6- and 30-month-old rats, resistance exercise
    Comparator
    Young rats
    Outcome group
    Aging markers · Aging and longevity

    Source sentences

    Summary
    RE induced increases in the mRNAs for IGF-I, mechano-growth factor, cyclin D1, and suppressor of cytokine signaling 3 were similar in old and young muscles.
    1 context sentence
    Summary · context
    Comparing 6- and 30-mo-old rats, the aims were to 1) determine whether these markers are altered with age and 2) identify age-sensitive responses to acute RE.

    This result measures the body's own MGF / PEG-MGF. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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