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Study · Non-randomized trial · n = 51 · 2005

1 result

Octreotide versus octreotide plus interferon-alpha in endocrine gastroenteropancreatic tumors: a randomized trial.

Arnold R, Rinke A, Klose KJ, Müller HH, Wied M, Zamzow K, Schmidt C, Schade-Brittinger C, Barth P, Moll R, Koller M, Unterhalt M and 4 more

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Hiddemann W, Schmidt-Lauber M, Pavel M, Arnold CN

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association1 Aug 2005Cited by 173 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients with progressive metastatic neuroendocrine tumors, median survival in the octreotide monotherapy arm was 32 months.

    In plain wordsIn patients with metastatic neuroendocrine tumors, median survival in the octreotide-only group was 32 months.

    Peptide
    Octreotide
    Outcome
    Not applicableMedian survival
    Study

    n = 51

    Outcome group
    Mortality · Cancer
    Studied dose
    Dose not stated

    Measurements

    Median survival
    32 months
    octreotide monotherapy arm

    Source sentences

    Summary
    Time to treatment failure and long-term survival did not differ significantly between the 2 groups, with a median survival of 32 and 54 months for the octreotide and the combination groups, respectively.
    2 context sentences
    Summary · context
    The effect of octreotide plus interferon-alpha versus octreotide monotherapy on the primary study end points of time to treatment failure (progression, death, stop of study treatment) and long-term survival was investigated in patients with progressive metastatic neuroendocrine foregut (mainly pancr…
    Summary · context
    One hundred nine of 125 registered patients were randomized starting in January 1995, and 105 patients (51 monotherapy, 54 combination treatment) were finally analyzed in March 2000.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:36 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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