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Study · Animal study (in vivo) · rabbit · 2005

2 results

Fluorescent microscopic study of epithalon binding in maternal and fetal rabbit tissues in health and under conditions of placental insufficiency.

Lapina EA, Nazarova LA, Petrova OP, Sibarov DA, Zubzhitskaya LB, Pavlova NG, Konstantinova NN, Konovalov YS, Kvetnoi IM, Arutyunyan AV, Grigorev EI

Bulletin of experimental biology and medicine1 May 2005Cited by 1 (Europe PMC)

PMID16224563 (opens in a new tab)DOI10.1007/s10517-005-0359-2 (opens in a new tab)PepBankPUB-16224563
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Pharmacokinetics

    In pregnant rabbits, dansil-labeled epithalon penetrated all tissues and organs of the mother and crossed the placenta into fetal organs.

    In plain wordsIn pregnant rabbits, labeled epithalon reached all tissues of the mother and crossed the placenta into the organs of the fetuses.

    Peptide
    Epitalon
    Outcome
    Not applicableTissue distribution of labeled epithalon
    Study

    rabbitn: not reported in source

    Pregnant rabbits and fetuses, normal and with placental insufficiency
    Outcome group
    Pharmacokinetics · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Epithalon (regulatory tetrapeptide) labeled with dansil (fluorescent stain) easily penetrates into all tissues and organs of pregnant rabbit females and through the placenta into fetal organs.
  2. 02AnimalAnimal study (in vivo)Pharmacokinetics

    In pregnant rabbits, labeled epithalon was incorporated into placental tissues more often in fetuses with placental insufficiency than in normal fetuses.

    In plain wordsIn pregnant rabbits, labeled epithalon was found in placental tissue more often with placental insufficiency than in normal pregnancies.

    Peptide
    Epitalon
    Outcome
    IncreaseIncorporation of labeled epithalon in placental tissue
    Study

    rabbitn: not reported in source

    Pregnant rabbits and fetuses, normal and with placental insufficiency
    Comparator
    Normal fetuses
    Outcome group
    Pharmacokinetics · Pharmacology
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Incorporation of labeled epithalon in placental tissues is more often observed in fetuses developing under conditions of placental insufficiency than in normal fetuses.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    9 Oct 2026, 18:17 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:47 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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