Study · Animal study (in vivo) · rat · 2005
5 resultsKohda Y, Kawai Y, Iwamoto N, Matsunaga Y, Aiga H, Awaya A, Gemba M
Biochemical pharmacology1 Nov 2005Cited by 15 (Europe PMC)
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Text rights: Publisher copyright. Results still quote short attributed sentences.
5 results from studies that gave the peptide. No result from this study comes from people.
In rats, FTS suppressed cisplatin-induced renal dysfunction.
In plain wordsIn rats, FTS reduced kidney dysfunction compared with cisplatin alone.
ratn: not reported in source
Cisplatin-induced nephrotoxicitySource sentences
FTS suppressed cisplatin-induced renal dysfunction and ERK activation in the kidney.
In rats, FTS suppressed cisplatin-induced renal ERK activation.
In plain wordsIn rats, FTS reduced kidney ERK activation compared with cisplatin alone.
ratn: not reported in source
Cisplatin-induced nephrotoxicitySource sentences
FTS suppressed cisplatin-induced renal dysfunction and ERK activation in the kidney.
In rats, FTS did not influence kidney platinum content after cisplatin administration.
In plain wordsIn rats, FTS did not change kidney platinum content compared with cisplatin alone.
ratn: not reported in source
Cisplatin-induced nephrotoxicitySource sentences
FTS did not influence any Pt contents in the kidney after cisplatin administration.
In rats, FTS alone increased HSP70 expression in the kidney cortex.
In plain wordsIn rats, FTS alone increased HSP70 expression in the kidney cortex.
ratn: not reported in source
Rat kidney cortex after FTS aloneSource sentences
The beneficial role of FTS against cisplatin nephrotoxicity may be mediated in part by HSP70, as suggested by its up-regulation in the kidney cortex treated with FTS alone.
In LLC-PK1 cells, FTS reduced cisplatin-induced injury.
In plain wordsIn cells, FTS reduced injury compared with cisplatin alone.
n: not reported in source
LLC-PK1 cells exposed to cisplatinSource sentences
In vitro treatment of LLC-PK1 cells with FTS significantly ameliorated cisplatin-induced cell injury.
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Version 2Current
21 Oct 2026, 15:58 UTC
Study results updated
Version 1
21 Oct 2026, 12:50 UTC
First added · source update from Europe PMC
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