In rat and mouse supraoptic nucleus, SK3 channels showed weak co-localization with oxytocin neurons but strong staining around them.
In plain wordsIn rats and mice, the SK3 channel marker was weak inside oxytocin cells and strong around them.
- Peptide
- Oxytocin
- Outcome
- Not applicableSK3 co-localization with oxytocin neurons in the SON
- Study
rat and mousen: not reported in source
supraoptic nucleus immunocytochemistry- Outcome group
- Receptor activity and mechanism · Nervous system and cognition
Source sentences
Double staining for oxytocin or vasopressin neurons revealed weak co-localization with SK3 but strong staining surrounding each neuron type.
1 context sentence(design, population, supporting numbers)
To determine the distribution of SK3 channels within the SON, we used immunocytochemistry in rats and in transgenic mice with a regulatory cassette on the SK3 gene, allowing regulated expression with dietary doxycycline (DOX).
In this study, Oxytocin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Oxytocin.