In normal and immunosuppressed mice, orally administered Talpha1 significantly increased CD8+ levels.
In plain wordsIn mice, thymosin alpha‑1 given by mouth raised CD8+ immune cells, in normal mice and in mice with a weakened immune system.
- Peptide
- Thymosin alpha-1
- Outcome
- IncreaseCD8+ level in normal and immunosuppressed mice
- Study
mousen: not reported in source
Normal and cyclophosphamide-immunosuppressed Balb/c mice- Comparator
- Empty yeast (negative control)
- Outcome group
- Immune response · Immune and inflammation
- Studied dose
- Dose not stated · oral (dried yeast)As given in this study (mouse).
Source sentences
In normal Balb/c mice or immune inhibition Balb/c mice, CD8(+) levels were significantly increased.
1 context sentence(design, population, supporting numbers)
Dried yeast containing three different concentration of Talpha1 was fed to normal Balb/c mice and other Balb/c mice whose immunities were inhibited in advance by cyclophosphamide.