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Study · Measured the body's own peptide · 2005

3 results

Expression and modulation of LL-37 in normal human keratinocytes, HaCaT cells, and inflammatory skin diseases.

Kim JE, Kim BJ, Jeong MS, Seo SJ, Kim MN, Hong CK, Ro BI

Journal of Korean medical science1 Aug 2005Cited by 60 (Europe PMC)

PMID16100459 (opens in a new tab)PMCIDPMC2782163 (opens in a new tab)DOI10.3346/jkms.2005.20.4.649 (opens in a new tab)PepBankPUB-16100459
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: CC BY-NC. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelObservational studyOther

    In skin biopsies from patients with psoriasis, immunohistochemistry showed abundant LL‑37 in the epidermis.

    In plain wordsIn skin samples from people with psoriasis, the body's own LL‑37 was abundant in the outer skin layer.

    Peptide
    LL-37
    Outcome
    Not applicableLL-37 in psoriasis epidermis
    Study

    n: not reported in source

    Outcome group
    Infection and antimicrobial activity · Skin and wound

    Source sentences

    Summary
    IHC analysis confirmed the presence of abundant LL-37 in the epidermis of psoriasis.
    1 context sentence
    Summary · context
    And expression of LL-37 in skin biopsy specimens from patients with atopic dermatitis and psoriasis was determined by immunohistochemical analysis.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Other

    In normal human keratinocytes, the body's own LL‑37 was expressed.

    In plain wordsIn lab-grown normal human skin cells, the body's own LL‑37 was made.

    Peptide
    LL-37
    Outcome
    Not applicableLL-37 expression in normal human keratinocytes
    Study

    humann: not reported in source

    Normal human keratinocytes
    Outcome group
    Infection and antimicrobial activity · Skin and wound

    Source sentences

    Summary
    In time-sequential analyses of LL-37 expression revealed that LL-37 was expressed in NHKs, but not in HaCaT cells.
    1 context sentence
    Summary · context
    Expressions of LL-37 in NHKs and HaCaT cells were evaluated by using RT-PCR, Western blotting, and immunohistochemical (IHC) staining at 6, 12, and 24 hr post stimulation after exposure to Ultraviolet B irradiation and lipopolysaccharide.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Other

    In HaCaT keratinocyte cells, LL‑37 was not expressed.

    In plain wordsIn lab-grown HaCaT skin cells, the body's own LL‑37 was not made.

    Peptide
    LL-37
    Outcome
    Not applicableLL-37 expression in HaCaT cells
    Study

    humann: not reported in source

    HaCaT cells
    Outcome group
    Infection and antimicrobial activity · Skin and wound

    Source sentences

    Summary
    In time-sequential analyses of LL-37 expression revealed that LL-37 was expressed in NHKs, but not in HaCaT cells.
    1 context sentence
    Summary · context
    Expressions of LL-37 in NHKs and HaCaT cells were evaluated by using RT-PCR, Western blotting, and immunohistochemical (IHC) staining at 6, 12, and 24 hr post stimulation after exposure to Ultraviolet B irradiation and lipopolysaccharide.

    This result measures the body's own LL-37. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    11 Oct 2026, 00:50 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 02:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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