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Study · Animal study (in vivo) · rat · 2005

3 results

The effects of oxytocin on the activity of cells in the anterior hypothalamus in experimental stress.

Mukhitdinova KhN, Stamova LG, Rasulov MM

Neuroscience and behavioral physiology1 Jun 2005

PMID16033194 (opens in a new tab)DOI10.1007/s11055-005-0081-6 (opens in a new tab)PepBankPUB-16033194
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In intact and stressed rats, intravenous oxytocin evoked different types of rearrangement of spike activity in anterior hypothalamic neurons.

    In plain wordsIn rats, oxytocin given into a vein changed the firing of hypothalamic nerve cells in different ways, in normal and stressed animals.

    Peptide
    Oxytocin
    Outcome
    MixedAnterior hypothalamic neuron spike activity after oxytocin
    Study

    ratn: not reported in source

    white laboratory rats, anterior hypothalamus neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · intravenousAs given in this study (rat).

    Source sentences

    Summary
    The results showed that oxytocin evoked different types of rearrangement of neuron activity both in intact and in stressed animals.
    1 context sentence
    Summary · context
    Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats, oxytocin dose-related effects altered the latent periods of anterior hypothalamic neuron responses and the nature of the spike-activity rearrangements.

    In plain wordsIn rats, different oxytocin doses changed how fast and in what way hypothalamic nerve cells responded.

    Peptide
    Oxytocin
    Outcome
    Not applicableDose-related neuron response latency and pattern
    Study

    ratn: not reported in source

    white laboratory rats, anterior hypothalamus neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · intravenousAs given in this study (rat).

    Source sentences

    Summary
    The dose-related effects of oxytocin affected the latent periods of neuron responses and the nature of rearrangements in spike activity.
    1 context sentence
    Summary · context
    Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin.
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In rats, anterior hypothalamic neurons with a higher baseline firing frequency responded less to oxytocin.

    In plain wordsIn rats, hypothalamic nerve cells that fired more often at rest reacted less to oxytocin.

    Peptide
    Oxytocin
    Outcome
    DecreaseNeuron response versus baseline firing frequency
    Study

    ratn: not reported in source

    white laboratory rats, anterior hypothalamus neurons
    Outcome group
    Receptor activity and mechanism · Nervous system and cognition
    Studied dose
    Dose not stated · intravenousAs given in this study (rat).

    Source sentences

    Summary
    The greater the frequency of the baseline activity of the cells, the less marked was the response of the neurons to administration of oxytocin.
    1 context sentence
    Summary · context
    Acute experiments on white laboratory rats were performed to study spike activity in neurons of the anterior hypothalamus in response to i.v. injections of different doses of oxytocin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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