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Study · Measured the body's own peptide · 2005

2 results

AVP- and OT-neurophysins response to apomorphine and clonidine in major depression.

Scantamburlo G, Hansenne M, Fuchs S, Pitchot W, Pinto E, Reggers J, Ansseau M, Legros JJ

Psychoneuroendocrinology1 Oct 2005Cited by 18 (Europe PMC)

PMID15964147 (opens in a new tab)DOI10.1016/j.psyneuen.2005.04.015 (opens in a new tab)PepBankPUB-15964147
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01HumanEndogenous levelNon-randomized trialMechanism

    In medication-free patients with major depression, OT-neurophysin responses to clonidine or apomorphine did not differ from those of healthy controls.

    In plain wordsIn people with depression, the body's own oxytocin marker did not respond differently from healthy people after the test drugs.

    Peptide
    Oxytocin
    Outcome
    No significant changeOT-neurophysin response to clonidine or apomorphine, depressed versus controls
    Study

    n = 50

    Comparator
    Healthy controls
    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    Concerning OT-neurophysins, no significant differences were found between depressed and controls in response to clonidine or apomorphine injections.
    1 context sentence
    Summary · context
    Apomorphine and clonidine tests were carried out in 25 medication-free depressive patients and 25 age and gender-matched healthy controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02HumanEndogenous levelNon-randomized trialMechanism

    In patients with major depression, acute apomorphine or clonidine injection did not change OT-neurophysin levels.

    In plain wordsIn people with depression, the test drugs did not change the body's own oxytocin marker.

    Peptide
    Oxytocin
    Outcome
    No significant changeOT-neurophysin change after acute apomorphine or clonidine in depressed patients
    Study

    n = 50

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    Moreover, we did not find any influence of acute apomorphine or clonidine injections on vasopressin-neurophysin or oxytocin-neurophysin in depressive patients.
    1 context sentence
    Summary · context
    Apomorphine and clonidine tests were carried out in 25 medication-free depressive patients and 25 age and gender-matched healthy controls.

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:51 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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