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Study · Non-randomized trial · n = 75 · 2005

4 results

Salmon calcitonin nasal spray treatment for postmenopausal women after hip fracture with total hip arthroplasty.

Peichl P, Marteau R, Griesmacher A, Kumpan W, Schedl R, Prosquil E, Fasol P, Bröll H

Journal of bone and mineral metabolism1 Jan 2005Cited by 15 (Europe PMC)

PMID15838628 (opens in a new tab)DOI10.1007/s00774-004-0591-2 (opens in a new tab)PepBankPUB-15838628
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In women after hip arthroplasty, calcitonin reduced bone turnover markers, further bone density loss and pain.

    In plain wordsIn women after hip replacement, calcitonin nasal spray was reported to reduce bone turnover markers, further bone density loss and pain.

    Peptide
    Calcitonin-salmon
    Outcome
    DecreaseBone turnover markers, bone density loss and pain
    Study

    n = 75

    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    200 IU twice daily in methods; 200 IU per day in results · intranasal · 12 monthsAs given in this study (human).

    Source sentences

    Summary
    Treatment with a salmon calcitonin nasal spray reduces bone turnover serum markers, loss of further bone density, and pain.
    2 context sentences
    Summary · context
    In an open study, 37 women who had undergone cementless total hip arthroplasty after accidental hip fractures were treated twice daily with 200 IU salmon calcitonin nasal spray for 12 months.
    Summary · context
    A parallel group of 38 women with a similar clinical status in terms of hip fractures and cementless total hip arthroplasty were treated with only one bag of 1000 mg calcium plus 880 IU vitamin D daily through the treatment period.
  2. 02HumanNon-randomized trialEfficacy outcome

    In women after hip arthroplasty, calcitonin promoted hip fracture repair.

    In plain wordsIn women after hip replacement, calcitonin was reported to promote the repair of hip fractures.

    Peptide
    Calcitonin-salmon
    Outcome
    IncreaseHip fracture repair
    Study

    n = 75

    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    200 IU twice daily in methods; 200 IU per day in results · intranasal · 12 monthsAs given in this study (human).

    Source sentences

    Summary
    Additionally, calcitonin promoted the repair of hip fractures and, as a coincidence finding, was associated with a significantly reduced rate of refractures as well as periprosthetic ossifications.
    2 context sentences
    Summary · context
    In an open study, 37 women who had undergone cementless total hip arthroplasty after accidental hip fractures were treated twice daily with 200 IU salmon calcitonin nasal spray for 12 months.
    Summary · context
    A parallel group of 38 women with a similar clinical status in terms of hip fractures and cementless total hip arthroplasty were treated with only one bag of 1000 mg calcium plus 880 IU vitamin D daily through the treatment period.
  3. 03HumanNon-randomized trialEfficacy outcome

    In women after hip arthroplasty, calcitonin was associated, as a coincidence finding, with a significantly reduced rate of refractures.

    In plain wordsIn women after hip replacement, calcitonin was linked to fewer repeat fractures than calcium and vitamin D alone, which the authors called a coincidence finding.

    Peptide
    Calcitonin-salmon
    Outcome
    DecreaseRefractures
    Study

    n = 75

    Comparator
    Calcium and vitamin D alone
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    200 IU twice daily in methods; 200 IU per day in results · intranasal · 12 monthsAs given in this study (human).

    Source sentences

    Summary
    Additionally, calcitonin promoted the repair of hip fractures and, as a coincidence finding, was associated with a significantly reduced rate of refractures as well as periprosthetic ossifications.
    2 context sentences
    Summary · context
    In an open study, 37 women who had undergone cementless total hip arthroplasty after accidental hip fractures were treated twice daily with 200 IU salmon calcitonin nasal spray for 12 months.
    Summary · context
    A parallel group of 38 women with a similar clinical status in terms of hip fractures and cementless total hip arthroplasty were treated with only one bag of 1000 mg calcium plus 880 IU vitamin D daily through the treatment period.
  4. 04HumanNon-randomized trialEfficacy outcome

    In women after hip arthroplasty, calcitonin was associated, as a coincidence finding, with a significantly reduced rate of periprosthetic ossifications.

    In plain wordsAfter hip replacement, calcitonin was linked to less bone formation around implants versus calcium and vitamin D alone, which authors called a coincidence finding.

    Peptide
    Calcitonin-salmon
    Outcome
    DecreasePeriprosthetic ossifications
    Study

    n = 75

    Comparator
    Calcium and vitamin D alone
    Outcome group
    Bone and joint · Musculoskeletal
    Studied dose
    200 IU twice daily in methods; 200 IU per day in results · intranasal · 12 monthsAs given in this study (human).

    Source sentences

    Summary
    Additionally, calcitonin promoted the repair of hip fractures and, as a coincidence finding, was associated with a significantly reduced rate of refractures as well as periprosthetic ossifications.
    2 context sentences
    Summary · context
    In an open study, 37 women who had undergone cementless total hip arthroplasty after accidental hip fractures were treated twice daily with 200 IU salmon calcitonin nasal spray for 12 months.
    Summary · context
    A parallel group of 38 women with a similar clinical status in terms of hip fractures and cementless total hip arthroplasty were treated with only one bag of 1000 mg calcium plus 880 IU vitamin D daily through the treatment period.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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