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Study · Measured the body's own peptide · 2005

2 results

Fos expression variances in mouse hypothalamus upon physical and osmotic stimuli: co-staining with vasopressin, oxytocin, and tyrosine hydroxylase.

Pirnik Z, Kiss A

Brain research bulletin1 May 2005Cited by 20 (Europe PMC)

PMID15833597 (opens in a new tab)DOI10.1016/j.brainresbull.2005.02.023 (opens in a new tab)PepBankPUB-15833597
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, hypertonic saline activated a larger share of oxytocin neurons in the PVN than immobilization did.

    In plain wordsIn mice, salt injection switched on more of the body's own oxytocin brain cells in the PVN than restraint did.

    Peptide
    Oxytocin
    Outcome
    IncreaseFos-positive oxytocin neurons in PVN
    Study

    mousen: not reported in source

    Hypertonic saline or immobilization stimulus
    Comparator
    Immobilization
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Measurements

    Fos-OXY perikarya after HS
    38 to 45%
    PVN
    Fos-OXY perikarya after IMO
    4 to 8%
    PVN

    Source sentences

    Summary
    In addition, in the PVN substantially more Fos-AVP (62-67% versus 10-15%) and Fos-OXY (38-45% versus 4-8%) perikarya were observed after HS than IMO, respectively.
    1 context sentence
    Summary · context
    was performed in response to physiologically two different, i.e. osmotic (i.p. hypertonic saline, HS) and immobilization (IMO), stimuli in mouse

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In mice, hypertonic saline activated more than 50% of oxytocin neurons in the SON, while immobilization activated less than 4%.

    In plain wordsIn mice, salt injection switched on many more of the body's own oxytocin brain cells in the SON than restraint did.

    Peptide
    Oxytocin
    Outcome
    IncreaseFos-positive oxytocin neurons in SON
    Study

    mousen: not reported in source

    Hypertonic saline or immobilization stimulus
    Comparator
    Immobilization
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In the SON, HS activated more than 50% of AVP and OXY neurons while IMO less than 4%.
    1 context sentence
    Summary · context
    was performed in response to physiologically two different, i.e. osmotic (i.p. hypertonic saline, HS) and immobilization (IMO), stimuli in mouse

    This result measures the body's own Oxytocin. Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:53 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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