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Study · Not a test of the peptide alone · 2005

3 results

Comparison of assays for determination of peptide content for lyophilized thymalfasin.

Vemuri S

The journal of peptide research : official journal of the American Peptide Society1 Apr 2005Cited by 11 (Europe PMC)

PMID15813890 (opens in a new tab)DOI10.1111/j.1399-3011.2005.00225.x (opens in a new tab)PepBankPUB-15813890
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone3

In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin alpha-1.

  1. 01LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    For thymalfasin peptide content, amino acid analysis was highly variable in one laboratory and quite precise in another.

    In plain wordsIn lab tests, one method for measuring thymalfasin content gave very different precision in two laboratories.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicablePeptide content by amino acid analysis
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    This study demonstrates that the AAA method is highly variable in one laboratory while quite precise in another laboratory.
    1 context sentence
    Summary · context
    Four independent methods were evaluated and compared to determine which would produce the best experimental precision for analysis of thymalfasin (thymosin alpha-1).

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  2. 02LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    For thymalfasin peptide content, HPLC results depended on the laboratory, with more precise values under cGMP.

    In plain wordsIn lab tests, an HPLC method for thymalfasin content gave results that depended on the laboratory.

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicablePeptide content by HPLC
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Source sentences

    Summary
    Similarly, HPLC results depended on the laboratory conducting the study with more precise values obtained under cGMP.
    1 context sentence
    Summary · context
    Four independent methods were evaluated and compared to determine which would produce the best experimental precision for analysis of thymalfasin (thymosin alpha-1).

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

  3. 03LabNot a test of Thymosin alpha-1 aloneIn vitro (cell-free)Other

    For thymalfasin peptide content, the CHN method gave highly precise values, with a coefficient of variation below 2%.

    In plain wordsIn lab tests, the CHN method measured thymalfasin content with high precision (coefficient of variation below 2%).

    Peptide
    Thymosin alpha-1
    Outcome
    Not applicablePeptide content by CHN elemental analysis
    Study

    n: not reported in source

    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Coefficient of variation
    < 2%
    CHN method

    Source sentences

    Summary
    On the contrary, the CHN method yielded highly precise [i.e. <2% coefficient of variation (CV)] values.
    1 context sentence
    Summary · context
    Four independent methods were evaluated and compared to determine which would produce the best experimental precision for analysis of thymalfasin (thymosin alpha-1).

    In this study, Thymosin alpha-1 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin alpha-1.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 3Current

    10 Oct 2026, 08:55 UTC

    Study results updated

  2. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  3. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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