In male rats with reduced pubococcygeus motoneuron stain after castration, PvN steroid block or spinal transection, intrathecal oxytocin recovered the reduction of the stain.
In plain wordsIn male rats, oxytocin given into the spinal canal restored a reduced motoneuron stain measure caused by castration, steroid block or spinal cord transection.
- Peptide
- Oxytocin
- Outcome
- IncreasePubococcygeus motoneuron stain recovery
- Study
ratn: not reported in source
Castrated, PvN steroid-blocked or T8-transected male rats- Outcome group
- Sex hormones and fertility · Reproductive and sexual health
- Studied dose
- Dose not stated · intrathecalAs given in this study (rat).
Source sentences
Data indicated that morphometric parameters of Pcm motoneurons were significantly reduced after castration or blocking of the steroids at the PvN site, or following complete transection of the spinal cord at the T8 level. In each case, the reduction of the stain was recovered after intrathecal treatment with oxytocin.
1 context sentence(design, population, supporting numbers)
Lumbosacral cord motoneurons innervating the pubococcygeus muscle (Pcm) at the pelvic floor of male rats were analyzed.