Skip to content

Study · Animal study (in vivo) · rat · 2005

1 result

Vasoactive intestinal peptide in the amygdala inhibits tail flick reflexes in rats.

Shin MS

Brain research1 Apr 2005Cited by 3 (Europe PMC)

PMID15804442 (opens in a new tab)DOI10.1016/j.brainres.2005.01.071 (opens in a new tab)PepBankPUB-15804442
Publisher pagePubMedAsk about this study
Jump to 1 result

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In anesthetized rats, bilateral application of VIP into the basolateral amygdala persistently suppressed radiant heat-evoked tail flick reflexes.

    In plain wordsIn rats, VIP placed in a brain region called the amygdala lastingly reduced the tail flick pain reflex.

    Peptide
    Vasoactive intestinal peptide (VIP, aviptadil)
    Outcome
    DecreaseRadiant heat-evoked tail flick reflex
    Study

    ratn: not reported in source

    anesthetized rats, radiant heat tail flick test
    Outcome group
    Pain · Nervous system and cognition
    Studied dose
    Dose not stated · bilateral application into the basolateral amygdalaAs given in this study (rat).

    Source sentences

    Summary
    Bilateral application of VIP into the basolateral region of the amygdala persistently suppressed radiant heat-evoked tail flick reflexes of anesthetized rats.
    1 context sentence
    Summary · context
    The present study was conducted to test the capability of a representative type of non-opioid peptides vasoactive intestinal peptide (VIP) in the amygdala to modulate nociception.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 12:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 12:41 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.