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Study · Not a test of the peptide alone · 2004

19 results

[Diabetes mellitus in elderly: geroprotective and antidiabetic properties of delta-sleep induced peptide].

Odin VI, Belikova TV, Pushkova ES, Barr NA

Advances in gerontology = Uspekhi gerontologii1 Jan 2004Cited by 1 (Europe PMC)

PMID15754961 (opens in a new tab)PepBankPUB-15754961

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study19

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone19

In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Delta sleep-inducing peptide (DSIP).

  1. 01HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, 60 days of Deltaran (a DSIP-containing drug) improved the SCAG score for impairment of recent memory (p=0.003).

    In plain wordsIn 11 elderly people with diabetes, memory problems scored better after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseSCAG impairment of recent memory
    Study

    n = 11

    Outcome group
    Cognition and memory · Nervous system and cognition

    Source sentences

    Summary
    After treatment were observed improvement of the parameters of quality of life on SCAG scale as the impairment of recent memory (p=0.003), mood depression (p=0.019), emotional lability (p=0.002) and anxiety (p=0.000).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  2. 02HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) improved the SCAG score for mood depression (p=0.019).

    In plain wordsIn 11 elderly people with diabetes, low mood scored better after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseSCAG mood depression
    Study

    n = 11

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    After treatment were observed improvement of the parameters of quality of life on SCAG scale as the impairment of recent memory (p=0.003), mood depression (p=0.019), emotional lability (p=0.002) and anxiety (p=0.000).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  3. 03HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) improved the SCAG score for emotional lability (p=0.002).

    In plain wordsIn 11 elderly people with diabetes, mood swings scored better after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseSCAG emotional lability
    Study

    n = 11

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    After treatment were observed improvement of the parameters of quality of life on SCAG scale as the impairment of recent memory (p=0.003), mood depression (p=0.019), emotional lability (p=0.002) and anxiety (p=0.000).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  4. 04HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) improved the SCAG score for anxiety (p=0.000).

    In plain wordsIn 11 elderly people with diabetes, anxiety scored better after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseSCAG anxiety
    Study

    n = 11

    Outcome group
    Anxiety and mood · Mental health and mood

    Source sentences

    Summary
    After treatment were observed improvement of the parameters of quality of life on SCAG scale as the impairment of recent memory (p=0.003), mood depression (p=0.019), emotional lability (p=0.002) and anxiety (p=0.000).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  5. 05HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) improved the quality of sleep (p=0.010).

    In plain wordsIn 11 elderly people with diabetes, sleep quality improved after treatment with the DSIP-containing drug Deltaran.

    Outcome
    IncreaseQuality of sleep
    Study

    n = 11

    Outcome group
    Sleep · Sleep

    Source sentences

    Summary
    Also were observed improvement of quality of sleep and felling between meals in treating patients (p=0.010).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  6. 06HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) improved the feeling between meals (p=0.010).

    In plain wordsIn 11 elderly people with diabetes, the feeling between meals improved after treatment with the DSIP-containing drug Deltaran.

    Outcome
    IncreaseFeeling between meals
    Study

    n = 11

    Outcome group
    Quality of life · Whole body

    Source sentences

    Summary
    Also were observed improvement of quality of sleep and felling between meals in treating patients (p=0.010).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  7. 07HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, the decrease of blood pressure with Deltaran (a DSIP-containing drug) was not significant.

    In plain wordsIn 11 elderly people with diabetes, blood pressure did not change significantly with the DSIP-containing drug Deltaran.

    Outcome
    No significant changeBlood pressure
    Study

    n = 11

    Outcome group
    Blood pressure · Cardiovascular

    Source sentences

    Summary
    decrease of BP (ns)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  8. 08HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, the increase of ABI with Deltaran (a DSIP-containing drug) was not significant.

    In plain wordsIn 11 elderly people with diabetes, the ankle-brachial index did not change significantly with the DSIP-containing drug Deltaran.

    Outcome
    No significant changeAnkle-brachial index (ABI)
    Study

    n = 11

    Outcome group
    Vascular function · Cardiovascular

    Source sentences

    Summary
    increase of ABI (ns)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  9. 09HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) increased pallesthesia (p=0.017).

    In plain wordsIn 11 elderly people with diabetes, vibration sense improved after treatment with the DSIP-containing drug Deltaran.

    Outcome
    IncreasePallesthesia (vibration sense)
    Study

    n = 11

    Outcome group
    Sensory perception · Nervous system and cognition

    Source sentences

    Summary
    increase of pallestesia (p=0.017)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  10. 10HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) decreased the frequency of microalbuminuria (p=0.011).

    In plain wordsIn 11 elderly people with diabetes, protein in urine was less frequent after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseFrequency of microalbuminuria (MAU)
    Study

    n = 11

    Outcome group
    Kidney function · Kidney and urinary

    Source sentences

    Summary
    decrease of MAU frequency (p=0.011)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  11. 11HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) decreased glycaemia levels after load (p=0.033).

    In plain wordsIn 11 elderly people with diabetes, blood sugar after a carbohydrate breakfast was lower after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseGlycaemia after carbohydrate load
    Study

    n = 11

    Outcome group
    Glycemic control · Metabolic and weight

    Source sentences

    Summary
    decrease of glycaemia levels after load (p=0.033)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  12. 12HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) decreased the basal blood level of growth hormone (p=0.034).

    In plain wordsIn 11 elderly people with diabetes, resting growth hormone was lower after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseBasal growth hormone level
    Study

    n = 11

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    decrease of basal and reactive levels in blood of growth hormone (p=0.034 and p=0.005 accord.)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  13. 13HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, Deltaran (a DSIP-containing drug) decreased the reactive blood level of growth hormone (p=0.005).

    In plain wordsIn 11 elderly people with diabetes, growth hormone after the breakfast test was lower after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseReactive growth hormone level
    Study

    n = 11

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    decrease of basal and reactive levels in blood of growth hormone (p=0.034 and p=0.005 accord.)
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  14. 14HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, the decrease of insulin level with Deltaran (a DSIP-containing drug) was not significant.

    In plain wordsIn 11 elderly people with diabetes, insulin levels did not change significantly with the DSIP-containing drug Deltaran.

    Outcome
    No significant changeInsulin level
    Study

    n = 11

    Outcome group
    Glycemic control · Endocrine and hormones

    Source sentences

    Summary
    And also after treatment were observed decrease of basal and reactive levels in blood of growth hormone (p=0.034 and p=0.005 accord.), insulin (ns), cortisol (ns) and on the contrary increase of dehydroepiandrosterone sulfate levels (ns).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  15. 15HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, the decrease of cortisol level with Deltaran (a DSIP-containing drug) was not significant.

    In plain wordsIn 11 elderly people with diabetes, cortisol did not change significantly with the DSIP-containing drug Deltaran.

    Outcome
    No significant changeCortisol level
    Study

    n = 11

    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    And also after treatment were observed decrease of basal and reactive levels in blood of growth hormone (p=0.034 and p=0.005 accord.), insulin (ns), cortisol (ns) and on the contrary increase of dehydroepiandrosterone sulfate levels (ns).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  16. 16HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In 11 elderly diabetic patients, the increase of dehydroepiandrosterone sulfate level with Deltaran (a DSIP-containing drug) was not significant.

    In plain wordsIn 11 elderly people with diabetes, dehydroepiandrosterone sulfate did not change significantly with the DSIP-containing drug Deltaran.

    Outcome
    No significant changeDehydroepiandrosterone sulfate level
    Study

    n = 11

    Outcome group
    Stress hormones · Endocrine and hormones

    Source sentences

    Summary
    And also after treatment were observed decrease of basal and reactive levels in blood of growth hormone (p=0.034 and p=0.005 accord.), insulin (ns), cortisol (ns) and on the contrary increase of dehydroepiandrosterone sulfate levels (ns).
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  17. 17HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In elderly diabetic patients who received only a diabetic diet, insulin resistance decreased with Deltaran (a DSIP-containing drug).

    In plain wordsIn elderly people with diabetes on diet only, insulin resistance fell after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseInsulin resistance in patients on diabetic diet only
    Study

    n: not reported in source

    Outcome group
    Glycemic control · Metabolic and weight

    Source sentences

    Summary
    Main positive change observed in patients received only diabetic diet, where was a decrease of insulin resistance and in patients with latent autoimmune diabetes (type LADA), where was a increase insulin secretion and decrease of daily dose of insulin requiring.
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  18. 18HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In elderly patients with latent autoimmune diabetes (LADA), insulin secretion increased with Deltaran (a DSIP-containing drug).

    In plain wordsIn elderly people with latent autoimmune diabetes, insulin secretion rose after treatment with the DSIP-containing drug Deltaran.

    Outcome
    IncreaseInsulin secretion in patients with LADA
    Study

    n: not reported in source

    Outcome group
    Glycemic control · Endocrine and hormones

    Source sentences

    Summary
    Main positive change observed in patients received only diabetic diet, where was a decrease of insulin resistance and in patients with latent autoimmune diabetes (type LADA), where was a increase insulin secretion and decrease of daily dose of insulin requiring.
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

  19. 19HumanNot a test of Delta sleep-inducing peptide (DSIP) aloneNon-randomized trialEfficacy outcome

    In elderly patients with latent autoimmune diabetes (LADA), the daily insulin dose needed decreased with Deltaran (a DSIP-containing drug).

    In plain wordsIn elderly people with latent autoimmune diabetes, the daily insulin dose needed fell after treatment with the DSIP-containing drug Deltaran.

    Outcome
    DecreaseDaily insulin dose in patients with LADA
    Study

    n: not reported in source

    Outcome group
    Glycemic control · Metabolic and weight

    Source sentences

    Summary
    Main positive change observed in patients received only diabetic diet, where was a decrease of insulin resistance and in patients with latent autoimmune diabetes (type LADA), where was a increase insulin secretion and decrease of daily dose of insulin requiring.
    1 context sentence
    Summary · context
    As the pilot study we examined 11 elderly diabetic patients (mean age 66.3 yr, BMI--28.5 kg/m2, duration of diabetes 12.5 yr). All patients receive 20 doses of DSIP-containing drug "Deltaran" daily. Tests was before and after 60 days after beginning treatment.

    In this study, Delta sleep-inducing peptide (DSIP) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Delta sleep-inducing peptide (DSIP).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    12 Oct 2026, 17:28 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:04 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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