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Study · Not a test of the peptide alone · 2004

4 results

Boxing as a sport activity associated with isolated GH deficiency.

Kelestimur F, Tanriverdi F, Atmaca H, Unluhizarci K, Selcuklu A, Casanueva FF

Journal of endocrinological investigation1 Dec 2004Cited by 85 (Europe PMC)

PMID15754728 (opens in a new tab)DOI10.1007/bf03345299 (opens in a new tab)PepBankPUB-15754728
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01HumanNot a test of GHRP-6 aloneObservational studyOther

    In boxers, peak GH after GHRH plus GHRP‑6 was lower than in matched non-boxing controls.

    In plain wordsBoxers had lower GH peaks after the combined test than matched non-boxing controls.

    Peptide
    GHRP-6
    Outcome
    DecreaseStimulated GH peak
    Study

    n = 18

    Comparator
    Non-boxing controls
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    GH peak
    10.9 microg/l
    boxers
    GH peak
    41.4 microg/l
    controls

    Source sentences

    Summary
    After GHRH+GHRP-6 test, mean peak GH level in boxers and in controls were 10.9 +/- 1.7 and 41.4 +/- 6.7 microg/l, respectively (p < 0.05).
    2 context sentences
    Summary · context
    Eleven actively competing or retired male boxers with a mean age of 38.0 +/- 3.6 yr and 7 age-, sex- and BMI-matched healthy non-boxing controls were included in the study.
    Summary · context
    To assess GH secretory status in boxers and healthy controls, GHRH (1 microg/kg)+GHRP-6 (1 microg/kg) test was performed.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02HumanNot a test of GHRP-6 aloneObservational studyOther

    In boxers, the GHRH plus GHRP‑6 test identified severe GH deficiency in 45%.

    In plain wordsThe combined test identified severe GH deficiency in 45% of boxers.

    Peptide
    GHRP-6
    Outcome
    Not applicableSevere GH deficiency
    Study

    n = 11

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    Severe GH deficiency
    45%
    boxers
    Boxers with severe GH deficiency
    5 boxers
    Peak GH below 10 microg/l

    Source sentences

    Summary
    Peak GH levels in 5 (45%) boxers were found to be lower than 10 microg/l and considered as severe GH deficient.
    2 context sentences
    Summary · context
    Eleven actively competing or retired male boxers with a mean age of 38.0 +/- 3.6 yr and 7 age-, sex- and BMI-matched healthy non-boxing controls were included in the study.
    Summary · context
    To assess GH secretory status in boxers and healthy controls, GHRH (1 microg/kg)+GHRP-6 (1 microg/kg) test was performed.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  3. 03HumanNot a test of GHRP-6 aloneObservational studyOther

    In boxers, GH peaks after the combined GHRH plus GHRP‑6 test correlated negatively with boxing duration.

    In plain wordsIn boxers, lower GH peaks after the combined test were linked to longer boxing duration.

    Peptide
    GHRP-6
    Outcome
    DecreaseGH peak and boxing duration
    Study

    n = 11

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    There was a significant negative correlation between peak GH levels and boxing duration, and between peak GH levels and number of bouts.
    2 context sentences
    Summary · context
    Eleven actively competing or retired male boxers with a mean age of 38.0 +/- 3.6 yr and 7 age-, sex- and BMI-matched healthy non-boxing controls were included in the study.
    Summary · context
    To assess GH secretory status in boxers and healthy controls, GHRH (1 microg/kg)+GHRP-6 (1 microg/kg) test was performed.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  4. 04HumanNot a test of GHRP-6 aloneObservational studyOther

    In boxers, GH peaks after the combined GHRH plus GHRP‑6 test correlated negatively with number of bouts.

    In plain wordsIn boxers, lower GH peaks after the combined test were linked to more bouts.

    Peptide
    GHRP-6
    Outcome
    DecreaseGH peak and number of bouts
    Study

    n = 11

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    There was a significant negative correlation between peak GH levels and boxing duration, and between peak GH levels and number of bouts.
    2 context sentences
    Summary · context
    Eleven actively competing or retired male boxers with a mean age of 38.0 +/- 3.6 yr and 7 age-, sex- and BMI-matched healthy non-boxing controls were included in the study.
    Summary · context
    To assess GH secretory status in boxers and healthy controls, GHRH (1 microg/kg)+GHRP-6 (1 microg/kg) test was performed.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Registered trials1

Trials this study reports on, or that list this study as a reference. Registry data from ClinicalTrials.gov.

1 trial · source ClinicalTrials.gov (opens in a new tab)

Status unknownPhase 2NCT04121780

Growth Hormone Replacement Therapy for Retried Professional Football Players

Center for Neurological Studiesn = 428 Oct 2019 to est. Sept 2026

TBI (Traumatic Brain Injury) · Concussion, Brain · Sport Injury · Anterior Pituitary Hyposecretion Syndrome · Hypopituitarism · Growth Hormone Deficiency

Trial pageClinicalTrials.govUpdated 8 Feb 2023

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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