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Study · Not a test of the peptide alone · 2005

2 results

3D molecular modeling, free radical modulating and immune cells signaling activities of the novel peptidomimetic L-glutamyl-histamine: possible immunostimulating role.

Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva EL, Alimbarova LM, Barinskii IP

Peptides29 Dec 2004Cited by 2 (Europe PMC)

PMID15752568 (opens in a new tab)DOI10.1016/j.peptides.2004.11.012 (opens in a new tab)PepBankPUB-15752568
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymogen (oglufanide).

  1. 01LabNot a test of Thymogen (oglufanide) aloneIn vitro (cells)Activity measurement

    In mononuclear cells, structural analogues including L-Glu-Trp stimulated thymidine incorporation compared with concanavalin A.

    In plain wordsIn cells, structural analogues including L-Glu-Trp increased thymidine incorporation compared with concanavalin A.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseThymidine incorporation
    Study

    n: not reported in source

    Mononuclear cells
    Comparator
    Mitogen concanavalin A
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The structural peptide-like analogues of L-Glu-Hist such as L-Glu-Trp, carcinine (beta-alanylhistamine), but not L-Pro-Glu-Trp were active in stimulating thymidine incorporation and in inducing proliferation of mononuclear cells as compared to mitogen concanavalin A at doses 2.5-25.0 microg/ml.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

  2. 02LabNot a test of Thymogen (oglufanide) aloneIn vitro (cells)Activity measurement

    In mononuclear cells, structural analogues including L-Glu-Trp induced proliferation compared with concanavalin A.

    In plain wordsIn cells, structural analogues including L-Glu-Trp increased proliferation compared with concanavalin A.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseMononuclear cell proliferation
    Study

    n: not reported in source

    Mononuclear cells
    Comparator
    Mitogen concanavalin A
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The structural peptide-like analogues of L-Glu-Hist such as L-Glu-Trp, carcinine (beta-alanylhistamine), but not L-Pro-Glu-Trp were active in stimulating thymidine incorporation and in inducing proliferation of mononuclear cells as compared to mitogen concanavalin A at doses 2.5-25.0 microg/ml.

    In this study, Thymogen (oglufanide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymogen (oglufanide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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