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Study · In vitro (cells) · 2005

2 results

Immunostimulating activities of the novel peptidomimetic L-glutamyl-histamine.

Babizhayev MA, Semiletov YA, Lul'kin YA, Sakina NL, Savel'yeva EL, Alimbarova LM, Barinskii IP

Clinical and experimental immunology1 Mar 2005

PMID15730390 (opens in a new tab)DOI10.1111/j.1365-2249.2004.02710.x (opens in a new tab)PepBankPUB-15730390
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabIn vitro (cells)Activity measurement

    In mononuclear cells, L-Glu-Trp stimulated thymidine incorporation compared with concanavalin A.

    In plain wordsIn cells, L-Glu-Trp stimulated thymidine incorporation compared with concanavalin A.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseThymidine incorporation
    Study

    n: not reported in source

    mononuclear cells
    Comparator
    Mitogen concanavalin A
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    2.5-25.0 microg/mlAs given in this study.

    Source sentences

    Summary
    The structural peptide-like analogues of L-Glu-Hist such as L-Glu-Trp, carcinine (beta-alanylhistamine), but not L-Pro-Glu-Trp were active in stimulating thymidine incorporation and in inducing proliferation of mononuclear cells compared to mitogen concanavalin A at doses 2.5-25.0 microg/ml.
  2. 02LabIn vitro (cells)Activity measurement

    In mononuclear cells, L-Glu-Trp induced proliferation compared with concanavalin A.

    In plain wordsIn cells, L-Glu-Trp induced cell multiplication compared with concanavalin A.

    Peptide
    Thymogen (oglufanide)
    Outcome
    IncreaseMononuclear cell proliferation
    Study

    n: not reported in source

    mononuclear cells
    Comparator
    Mitogen concanavalin A
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    2.5-25.0 microg/mlAs given in this study.

    Source sentences

    Summary
    The structural peptide-like analogues of L-Glu-Hist such as L-Glu-Trp, carcinine (beta-alanylhistamine), but not L-Pro-Glu-Trp were active in stimulating thymidine incorporation and in inducing proliferation of mononuclear cells compared to mitogen concanavalin A at doses 2.5-25.0 microg/ml.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 12:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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