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Study · Animal study (in vivo) · mouse · 2005

1 result

Hypothalamic growth hormone-releasing hormone (GHRH) deficiency: targeted ablation of GHRH neurons in mice using a viral ion channel transgene.

Le Tissier PR, Carmignac DF, Lilley S, Sesay AK, Phelps CJ, Houston P, Mathers K, Magoulas C, Ogden D, Robinson IC

Molecular endocrinology (Baltimore, Md.)20 Jan 2005Cited by 31 (Europe PMC)

PMID15661833 (opens in a new tab)DOI10.1210/me.2004-0223 (opens in a new tab)PepBankPUB-15661833
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In GHRH-M2 mice, acute intravenous GHRP‑6 did not elicit a significant GH response.

    In plain wordsIn mice with silenced or ablated GHRH neurons, intravenous GHRP‑6 did not produce a significant GH response.

    Peptide
    GHRP-6
    Outcome
    No significant changeAcute GH response
    Study

    micen: not reported in source

    GHRH-M2 transgenic mice
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    Dose not stated · intravenousAs given in this study (mice).

    Source sentences

    Summary
    Acute iv injections of GHRH in GHRH-M2 mice elicited a significant GH response, whereas injections of GHRP-6 did not.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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