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Study · Randomized controlled trial · n = 94 · 2005

3 results

Oxytocin during myomectomy: a randomized study.

Agostini A, Ronda I, Franchi F, Bretelle F, Roger V, Cravello L, Blanc B

European journal of obstetrics, gynecology, and reproductive biology1 Feb 2005Cited by 24 (Europe PMC)

PMID15653210 (opens in a new tab)DOI10.1016/j.ejogrb.2004.06.032 (opens in a new tab)PepBankPUB-15653210
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In women having myomectomy, oxytocin did not change peroperative blood loss compared with placebo.

    In plain wordsIn women having myomectomy, oxytocin did not reduce blood loss during surgery compared with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changePeroperative blood loss during myomectomy
    Study

    n = 94

    Comparator
    Placebo
    Analysis
    Primary
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    Dose not stated

    Measurements

    Blood loss
    508 ml
    oxytocin group
    Blood loss
    451 ml
    placebo group

    Source sentences

    Summary
    Peroperative blood loss was no different between the oxytocin group and the placebo group (508 +/- 558 ml versus 451 +/- 336 ml; P=0.55).
    2 context sentences
    Summary · context
    From October 1998 to May 2002, 94 patients requiring surgical myomectomy by laparotomy or by the vaginal approach were enrolled in a randomized double blind study.
    Summary · context
    In the first group (47 patients) oxytocin was administered during myomectomy and in the second group (47 patients) a placebo was used.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In women having myomectomy, the rate of blood transfusion was similar with oxytocin and placebo.

    In plain wordsIn women having myomectomy, blood transfusion was needed about as often with oxytocin as with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeRate of blood transfusion
    Study

    n = 94

    Comparator
    Placebo
    Analysis
    Primary
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Rates of autotransfusion and blood transfusion were also similar in both groups
    2 context sentences
    Summary · context
    From October 1998 to May 2002, 94 patients requiring surgical myomectomy by laparotomy or by the vaginal approach were enrolled in a randomized double blind study.
    Summary · context
    In the first group (47 patients) oxytocin was administered during myomectomy and in the second group (47 patients) a placebo was used.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In women having myomectomy, the rate of autotransfusion was similar with oxytocin and placebo.

    In plain wordsIn women having myomectomy, autotransfusion was needed about as often with oxytocin as with placebo.

    Peptide
    Oxytocin
    Outcome
    No significant changeRate of autotransfusion
    Study

    n = 94

    Comparator
    Placebo
    Analysis
    Primary
    Outcome group
    Bleeding and clotting · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Rates of autotransfusion and blood transfusion were also similar in both groups.
    2 context sentences
    Summary · context
    From October 1998 to May 2002, 94 patients requiring surgical myomectomy by laparotomy or by the vaginal approach were enrolled in a randomized double blind study.
    Summary · context
    In the first group (47 patients) oxytocin was administered during myomectomy and in the second group (47 patients) a placebo was used.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    11 Oct 2026, 20:03 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 02:50 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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