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Study · Not a test of the peptide alone · 2004

2 results

Growth hormone (GH) peaks versus areas under the curve in the diagnosis of adult GH deficiency: analysis of the variables provided by the GHRH + GHRP-6 test.

Koppeschaar HP, Popovic V, Leal A, Otero XL, Torres E, Paramo C, Micic D, Garcia-Mayor RV, Sartorio A, Dieguez C, Casanueva FF

Pituitary1 Jan 2004Cited by 5 (Europe PMC)

PMID15638293 (opens in a new tab)DOI10.1023/b:pitu.0000044629.10484.40 (opens in a new tab)PepBankPUB-15638293
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking GHRP-6.

  1. 01HumanNot a test of GHRP-6 aloneObservational studyActivity measurement

    In adults assessed with the GHRH plus GHRP‑6 test, basal GH lacked diagnostic capability.

    In plain wordsBasal GH did not identify GH deficiency in adults assessed with the combined test.

    Peptide
    GHRP-6
    Outcome
    Not applicableBasal GH diagnostic capability
    Study

    n = 330

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Source sentences

    Summary
    Under ROC curve analysis, the basal variable was devoid of diagnostic capability
    1 context sentence
    Summary · context
    146 patients with GH deficiency due to organic pituitary disease and 184 healthy subjects were administered GHRH 1 microg/Kg iv, plus GHRP-6 1 microg/Kg iv, and GH was determined.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

  2. 02HumanNot a test of GHRP-6 aloneObservational studyActivity measurement

    In adults, GH peak and AUC after GHRH plus GHRP‑6 had similar diagnostic accuracy.

    In plain wordsIn adults, the combined test's GH peak and AUC had similar diagnostic accuracy.

    Peptide
    GHRP-6
    Outcome
    No significant changeGH peak ROC area
    Study

    n = 330

    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones

    Measurements

    ROC area
    0.9997
    GH peak
    ROC area
    0.9993
    AUC

    Source sentences

    Summary
    while the other variables performed strikingly well, the ROC curve area for the GH peak was 0.9997; and for the AUC 0.9993, with no statistical differences.
    1 context sentence
    Summary · context
    146 patients with GH deficiency due to organic pituitary disease and 184 healthy subjects were administered GHRH 1 microg/Kg iv, plus GHRP-6 1 microg/Kg iv, and GH was determined.

    In this study, GHRP-6 was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking GHRP-6.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    21 Oct 2026, 15:58 UTC

    Study results updated

  2. Version 1

    9 Oct 2026, 03:13 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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