Skip to content

Study · Case report or series · n = 1 · 2004

3 results

Hypogonadism in a patient with a mutation in the luteinizing hormone beta-subunit gene.

Valdes-Socin H, Salvi R, Daly AF, Gaillard RC, Quatresooz P, Tebeu PM, Pralong FP, Beckers A

The New England journal of medicine1 Dec 2004Cited by 75 (Europe PMC)

PMID15602022 (opens in a new tab)DOI10.1056/nejmoa040326 (opens in a new tab)PepBankPUB-15602022
Source linkPubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In a man with an LH beta-subunit mutation and hypogonadism, hCG increased circulating testosterone.

    In plain wordsIn a man with an LH gene mutation and hypogonadism, hCG increased blood testosterone.

    Peptide
    hCG (human chorionic gonadotropin)
    Outcome
    IncreaseCirculating testosterone
    Study

    n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treatment with human chorionic gonadotropin increased circulating testosterone, promoted virilization, and was associated with the appearance of normal spermatozoa in low concentrations.
    1 context sentence
    Summary · context
    A 30-year-old man who presented with delayed puberty and infertility was found to have hypogonadism associated with an absence of circulating luteinizing hormone.
  2. 02HumanCase report or seriesEfficacy outcome

    In a man with an LH beta-subunit mutation and hypogonadism, hCG promoted virilization.

    In plain wordsIn a man with an LH gene mutation and hypogonadism, hCG promoted male sexual development.

    Peptide
    hCG (human chorionic gonadotropin)
    Outcome
    IncreaseVirilization
    Study

    n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treatment with human chorionic gonadotropin increased circulating testosterone, promoted virilization, and was associated with the appearance of normal spermatozoa in low concentrations.
    1 context sentence
    Summary · context
    A 30-year-old man who presented with delayed puberty and infertility was found to have hypogonadism associated with an absence of circulating luteinizing hormone.
  3. 03HumanCase report or seriesEfficacy outcome

    In a man with an LH beta-subunit mutation and hypogonadism, hCG treatment was associated with normal spermatozoa appearing in low concentrations.

    In plain wordsIn a man with an LH gene mutation and hypogonadism, hCG treatment was linked to normal sperm appearing at low concentrations.

    Peptide
    hCG (human chorionic gonadotropin)
    Outcome
    IncreaseNormal spermatozoa appearance
    Study

    n = 1

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treatment with human chorionic gonadotropin increased circulating testosterone, promoted virilization, and was associated with the appearance of normal spermatozoa in low concentrations.
    1 context sentence
    Summary · context
    A 30-year-old man who presented with delayed puberty and infertility was found to have hypogonadism associated with an absence of circulating luteinizing hormone.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.